Science journalism by Leonid Schneider, on research integrity and academic publishing in life sciences and biomedicine
Patricia Murray uncovers the business secrets of the Nobelist Martin Evans and his partner Ajan Reginald. It seems the magic iMP cells used to treat patients in Greece were drawn from the blood of patients in Swansea, for the purpose of a secret PhD thesis. There is no serious science behind it, only serious investor money and a fraudulent patent.
Dentistry professors at UCLA published manipulated data in top-level journals. When a colleague reported them, the university retaliated against the whistleblower.
Sir Martin Evans, winner of Nobel prize 2007, founded in 2009 the stem cell start-up Celixir, together with a struck-off dentist Ajan Reginald. With the help of the British heart surgeon Stephen Westaby, they ran a very profitable clinical trial in Greece, which now moved into UK.
The 2008 Lancet paper of Paolo Macchiarini and Martin Birchall about the world first trachea transplant might end up retracted. Until recently, the journal’s editor Richard Horton used to ignore and suppress “non peer-reviewed” evidence, but due to combined pressure of activism, media and politics, things started to move.
In yet another investigation, UCL whitewashed Martin Birchall of all responsibilities. I publish here the confidential report and excerpts from a secret PhD thesis, which the UCL committee carefully avoided to read.
The 2015 Nature Cell Biology paper by the Spanish cancer researcher Carlos Lopez-Otin and his US partner George Q Daley, stem cell titan and dean of Harvard Medical School, is being retracted. First author and Lopez-Otin’s student Clara Soria-Valles caused Daley even more trouble: her next groundbreaking paper was meant to be already published, but it is not even submitted and might never be.
Paediatric surgeon Paolo De Coppi claims to grow all possible internal organs in his lab at UCL. Though his career started with his association with Macchiarini, and their regenerative medicine ideas sound strangely similar, De Coppi is celebrated as a modest genius poised to save lives of uncounted children, and the funding money flows.
A “defamation Complaint” was lodged with Google, against 6 of my articles and one cartoon. Each of them affects to some degree the British laryngologist Martin Birchall, professor at UCL and former close associate of scandal surgeon Paolo Macchiarini. I also show that Birchall and UCL even now continue researching plastic tracheas on pigs, for future use in humans patients. This grant is presently funded by UK government.
This is my review of the Russian book “Megagrant”, which tells of Macchiarini’s adventures with the plastic trachea, much of it played out in Russia, funded by a state Megagrant of €4.5mn. Some books are namely only good as court evidence.
Elite journal Nature Cell Biology (NCB) requests deposition of raw data, in particular original scans of western blots and other gel analyses. Spanish star cancer researcher Carlos López-Otín, winner of 2017 Nature Mentoring Award, instead deposited whatever odd gel picture his lab had available, counting that nobody will bother to check. Yet readers did.
