The hammer has fallen. The lab of misconduct-tainted plant scientist Patrice Dunoyer at the CNRS Institut de Biologie Moléculaire des Plantes (IBMP) in Strasbourg, France, has been closed with a 48 hour notice, following the decision of the institute’s director Laurence Maréchal-Drouard. The (now former) lab members were informed by general mailing list announcement; the reasons for closure were officially “not related to integrity concerns”. The only good news for Dunoyer is that he is tenured, and cannot be sacked for his previous research misconduct, because CNRS already punished him for it with a whole one-month suspension.
Game over apparently near for the indestructible Swedish regenerative medicine researcher Suchitra Sumitran-Holgersson, after investigations at her University of Gothenburg draw to an end. It is about experimental transplants of decellurised veins “regenerated” with the patient’s own bone marrow cells into three child patients, all of whom ended up in life-long medical care, one patient received a liver transplant after her graft failed, another child suffered severe complications (see this earlier report about an external investigation by Bengt Gerdin into that matter). The University of Gothenburg then established an investigative committee, which followed up on the Gerdin report and specific concerns voiced by a journal editor and a colleague. I publish below the two decisions which revealed that Sumitran-Holgersson and her surgeon partner Michael Olausson never performed any animal testing before recruiting their human patients, they also failed to obtain ethics permits for these operations. Instead the two lied in their publications (Olausson et al, Lancet, 2012; Olausson et al EBioMedicine, 2014) about having obtained ethics votes (something I already uncovered before). During the investigation, Olausson and Sumitran-Holgersson were caught submitting false information to the committee. They were now found guilty of misconduct and ethics breach in both these publications. Continue reading “Sumitran-Holgersson and Olausson guilty of misconduct and unethical experiments on children”
The misconduct-tainted paper on oesophagus transplants in rats (Sjöqvist et al 2014) by the fallen star of regenerative medicine Paolo Macchiarini is finally retracted by the journal Nature Communications. This happens after Swedish investigations found the authors (primarily the scandal thorax surgeon and his right-hand man Philipp Jungebluth) guilty of data manipulation and research misconduct in September 2016 and after the Karolinska Institutet (KI) shortly before Christmas publicly demanded a retraction (see my report here). Today’s retraction is a major setback for Macchiarini, since his current employment and funding at the Federal University of Kazan (KFU) in Russia depend on his experiments with oesophageal transplants in primates (see my reports here and here). That Russian project was in turn only possible because of Macchiarini’s allegedly successful experiments in rats, published in a prestige journal with “Nature” in its title. This paper’s retraction is therefore probably only the beginning of a whole looming avalanche of bad news for Macchiarini and his acolyte Jungebluth (who currently sues me in court). An expert review of their publication Jungebluth et al 2015 declares the findings of misconduct, ethics breach and patient abuse. The report however has yet to be confirmed by a commission at the Swedish Central Ethics Review Board (CEPN) and then formulated as an official decree by the KI. I publish the expert reviewer report below. Continue reading “Retraction, and another looming misconduct finding for Macchiarini and Jungebluth”
The University of Würzburg did not ignore the Open Letter in support of my journalism, and has concluded its internal investigation into medical and scientific activities of their trachea transplanters Heike and Thorsten Walles, without finding any misconduct. This was however not the end of it. I was invited to appeal this decision in front of the commission, which I did on March 6th 2017. In the end, the medical “external consultant”, Roland Jahns (specialist in inner medicine from the University Clinic of Würzburg) was catapulted out of the commission after insulting me as “pseudoscientist” and the entire investigation will be re-opened, with a new consultant to be recruited. The main reason: a newly emerged wealth of evidence of gross data manipulations in the papers by Walles, which readers of my site posted on PubPeer just when I arrived in Würzburg to give evidence.
During my discussion with the Standing Commission for the Investigation of Scientific Misconduct of the University of Würzburg on March 6th, I was also told that the commission does not see my original text, for which I am facing a court trial on March 16th, as factually wrong. All information provided there was deemed correct except of one aspect: my readers were said to be led to misunderstand that the trachea transplant operations took place in Würzburg (while they happened in Stuttgart). The commission made clear that their university does not want to be associated with these transplants. They did however admit that the misunderstanding arose because Walles themselves have been placing such false information in media (including this recent article in the Siemens magazine), and even on the University of Würzburg website. The commission however assigned to me the responsibility of checking in advance the truthfulness of such obscure sources. Continue reading “Würzburg misconduct Commission acquits Walles, dismisses biased medical expert, restarts anew as data manipulations flood in”
The Spanish zombie scientist Susana González, former star of regenerative medicine and ageing research, now retracts two papers in Nature Communications, after she only recently retracted a paper in Cell Cycle. The responsibility for the absence of original data and data manipulations is with her. She also recently lost her court case against her sacking with the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid, though this may go into the next court instance. Her ERC research grant of €2 Million remains suspended. I previously reported about this and Gonzalez’s data integrity issues as well as her sacking from CNIC, and later on about her new job with Centro de Biología Molecular Severo Ochoa (CBMSO), also in Madrid. It seems at the present stage, Gonzalez is out on her ear of doing research, but certainly not out of being employed in academic research in Spain. Continue reading “Three retractions and lost court case for zombie Susana Gonzalez”
There is a popular saying: “A fish stinks from the head down”. This is what the situation starts to look like for French CNRS Institut de Biologie Moléculaire des Plantes (IBMP) in Strasbourg, also unofficially known as “The Olivier Voinnet Institute for Research Integrity in Plant Sciences”, after its most famous former research director. A publication from the lab of the institute’s head, Laurence Maréchal-Drouard, seems to contain evidence of inappropriate data manipulation. The gel shown in Figure 1A of Salinas et al 2014, seems to have “no less than 4 copies of a background patch”, according to a concerned reader who contacted me with this evidence. Drouard herself did not reply to my email, possibly because she and her entire CNRS institute are banned from communicating with me.
Antonia Joussen, German professor and head of the ophthalmology clinic at the Berlin university hospital Charite, is innocent of research misconduct in any form, despite of all the evidence of data irregularities in her publications which emerged in 2015 on PubPeer (see my detailed report here). This is at least what the German Research Foundation (DFG) decided two weeks ago, despite never disputing the PubPeer evidence and even admitting that some of Joussen’s publications do contain manipulated figures. There however, DFG decided that it was Joussen’s co-authors who secretly manipulated the data without her knowing, while her authorship on these problematic papers was anyway accidental and attributed to her behind her back as well. With such argumentation, even as a senior researcher Joussen was not supposed to ensure the data integrity in her own papers. Continue reading “DFG decision: Antonia Joussen innocent victim of co-authors’ data manipulations”