German academic jargon has a peculiar expression: Doktorvater. It means “doctoral father”, a fatherly figure who takes his helpless PhD student progeny by the hand and guides and teaches the offspring of his academic loins the wisdom of science, up to the graduation. Nowadays with the system being less patriarchal, one can instead have the figure of a Doktormutter, doctoral mother. Which obviously doesn’t bring same gravitas or inspires same respect and awe, and is therefore hardly ever used.
The German diabetologist and Professor and University of Bremen Kathrin Maedler is a central figure of an academic dynasty. Using Photoshop simulations (read here), she discovered a cure for diabetes via inhibition of the inflammatory cytokine interleukin-1-beta (IL-1β), which was then confirmed as a definite cure for diabetes in clinical trials led by her own Swiss Doktorvater Marc Donath, then professor at University of Zürich, now in Basel. Over 15 years later, the Maedler-Donath cure was proven as utterly ineffective against hypoglycaemia and diabetes by same Donath, in another clinical trial. Because of her Photoshop creativity with discovering diabetes cures and ensuing retractions, Donath’s past PhD student Maedler was asked by the German Research Council DFG to surrender her prestigious Heisenberg professorship, while the German Diabetes Society (DDG) revoked her Ferdinand Bertram Prize from 2011 (read here). Since 2017, her PhD thesis is again under investigation of University of Zürich.
That diabetes research was also what made the career of Maedler’s own PhD student,Amin Ardestani, presently junior research group leader at the University of Bremen. His thesis received an award from the local Rotary Club, of course also Ardestani got a prize from DDG, which he also saw revoked for engaging into same activities as his Doktormutter. Still, he is still receiving awards, including from Elsevier. I will present below some data irregularities and unacknowledged textual reuse from Ardestani’s 2013 PhD thesis, which was supervised by Maedler.
It is now quasi official: do not mess with Frontiers. My earlier reporting made it a credible possibility that this Swiss publisher was behind the January 2017 shut-down and removal of Jeffrey Beall’s list of “potential, possible, or probable predatory scholarly open-access publishers”, and it was now indeed verified by an article in Chronicle of Higher Education. The librarian Beall used to be constantly under attack from Open Access (OA) publishers who were unhappy about his personal opinions and his private decisions to place them on his blog list. With those, his University of Colorado in Denver supported Beall. But the trouble started when he placed in October 2015 the Swiss publisher Frontiers onto his list, thus effectively declaring this Holtzbrinck-owned outlet a predatory publisher, after hearing of scientists’ complaints and reading my reports. To be fair, Frontiers are still defended by a much bigger number of scientists who see the advantage of having a reliable business partner who will publish certain manuscripts which hardly any respectable journal might consider. Especially certain kinds of psychologists figured out that with the life-science-oriented Frontiers they can easily get merited as proper neuroscientists, or even biomedical polymaths (e.g., here). Regardless of the bunk they place there for $2500 a pop.
Frontiers first tried it nicely with Beall, when the Chief Executive Officer Frederick Fenter and journal manager Mirjam Curno (who is also trustee at Committee for Publication Ethics, COPE, read here) visited the librarian before Christmas 2016 in Denver (see my report here). Since Beall still did not remove Frontiers from his list, Fenter rallied its loyal journal editors and started together with them in August 2016 a campaign against Beall, demanding that his university punishes the librarian or at least forces him to remove Frontiers from his private list (read here). That information on my site served as (utterly uncredited) template for the aforementioned Chronicle of Higher Education article (as its author Paul Basken admitted to me, but his editor Brock Read denied). Basken then contacted Beall, who then also revealed to him that in January 2016 the University of Colorado Denver caved in to Frontiers demands and opened a misconduct case against its librarian. At this point, Beall decided to delete his list and save his job. An academic disagreement was resolved in a honed and cherished academic tradition: with a call to the employer and a threat of sacking.
Christmas season is the time to eat lots of chocolate. And as science teaches us, your confectionery is actually the superfood which will make you healthy, slim and clever. Good for you, good for the chocolate industry which often generously sponsors such scientists.
The prize-winning German pharmacologist and diabetes researcher Kathrin Maedler is regularly in the German and international news, either as a celebrated genius about to cure diabetes or as a potential cheater, responsible for masses of duplicated images in her publications. The rectorate of her own University of Bremen absolved their professor of all suspicions of data manipulations, while admitting image duplications and loss of original data. One argument was that all results were successfully reproduced, yet by whom: that the Bremen rectorate prefers not to answer, together with all other relevant questions which would have made this investigation anywhere credible. In the same vein, another investigation at the University of Zürich in Switzerland, where Maedler did her PhD in 2000-2004 under the supervision of Marc Donath, absolved them both of any suspicion of misconduct as well, while refusing to provide any further explanations. Meanwhile, other labs have refuted Maedler’s discoveries, but these publications were dismissed by the University of Bremen as irrelevant. Maedler also had to retract a publication Ardestani et al 2011 from the Journal of Biological Chemistry (which is known to have a rather tough stance on suspected misconduct). Continue reading “Kathrin Maedler: persecuted genius or zombie scientist?”→
Great scientists never have any conflicts of interests, and in the case of the investigation of the research misconduct by the plant scientist Olivier Voinnet, led by his Swiss employer ETH Zürich, this was also apparently the case. Voinnet was found guilty of misconduct and admitted image manipulations in many papers. Yet his science remained largely unquestioned, and even original data behind the most outrageously manipulated figures was said to have been available in many cases. The ETH investigation recommended 6 retractions, one of which was even avoided thanks to the concerns the journal Science had towards that paper’s junior authors (Voinnet’s current retraction count stands at 8 papers and almost 20 corrections, where manipulated data was simply exchanged with new one). Professor emeritus Witold Filipowicz, of the Friedrich-Mieschner-Institute in Basel, is like Voinnet a specialist in the field of regulatory small RNAs, and he was therefore one of two external Voinnet investigators whom ETH invited in early 2015. It did not matter to ETH that it was actually Filipowicz who nominated Voinnet for the EMBO Gold Medal, which the disgraced plant scientist then lost after EMBO’s own investigation into his many years of data manipulation. Continue reading “The Voinnet investigator and the tricky issue of conflict of interests”→
Another retraction hits the fallen star plant scientist Olivier Voinnet. This time it is a previously corrected paper in Science, which was pulled after new evidence of further data manipulations appeared on PubPeer some months after its 3rd correction.
This makes it Voinnet’s 8th retraction, but the loss of the Dunoyer et al 2010 paper is more than just another brick falling from his great publishing record edifice. It is one of the two pillars of an entire school of thought in the field of plant pathogen defence, which we now witness crumbling into dust (see my earlier report and a brief summary below).
The Dunoyer et al 2010 paper has been corrected twice before (both are behind paywall, the one from April 15th 2011 acknowledges image reuse: “The image in Fig. 3B (center panel) was previously published as Fig. 1e in P. Dunoyer et al., Nat. Genet. 39, 848 (2007)”). The third correction from January 22nd 2016 declared a shopping list of further image irregularities, with Patrice Dunoyer taking full responsibility, just like he did on many other occasions (see my earlier report here).
The Swiss publishing business Frontiers was placed by the US librarian Jeffrey Beall on his well-known and hotly disputed list as “potential, possible or probable predatory publisher”. Frontiers however was not prepared to take this lying down. The publisher’s Executive Editor Frederick Fenter first tried it nicely. Shortly before Christmas 2015, he flew to visit Beall at his University of Colorado in Denver, with the senior manager Mirjam Curno in tow. Curno is incidentally also board member and trustee of the Committee on Publication Ethics (COPE). Afterwards, Fenter stopped being nice. In August 2016, he bombarded around ten senior officials at the University Colorado in Denver with letters and a dossier (see below) demanding that they make sure Frontiers is removed from their employee’s private list.
OA publisher Frontiers added to list of questionable publishers, following wide disapproval from scientists. http://t.co/HHJTksXtb4#OA
Thing is: University of Colorado has nothing to do with the so-called Beall’s List. The list is part of the librarians private blog on WordPress (same platform I use). In fact, this is the disclaimer which Beall placed on his site clear for all to see:
“These views represent the personal opinions of the author (Jeffrey Beall) and may not reflect the position of the University of Colorado Denver or the University of Colorado System”.