Open Letter in support of my investigation of trachea transplants in Germany, by Rafael Cantera

Below a support letter by Rafael Cantera, professor of zoology at the University of Stockholm in Sweden, addressed to the leadership of the University Clinic Würzburg. This is because two professors of this German university, Thorsten Walles and Heike Mertsching (now Walles) chose to respond to my inquiries about their earlier trachea transplants made from pig intestine with lawyers’ financial blackmail and right after, with court actions, which had me sentenced guilty and a potential prison term of 6 months, without my prior knowledge. Such are the peculiarities of German law: internet bloggers are basically  legally defined here by default as criminals, and professors as infallible and divine beings (in fact, even Walleses’ former boss and collaborator Paolo Macchiarini is still a protected adjunct professor at their former common place of work, the Medical University Hannover). I received lots of support from my readers, and was also invited to give an interview with the French magazine Mediapart (German version here). Now, I am deeply grateful to Prof. Cantera for his support, and hope other international and maybe even German academics join in and sign below.  Continue reading “Open Letter in support of my investigation of trachea transplants in Germany, by Rafael Cantera”

The western blot doctors of Silesia

The western blot doctors of Silesia

Protein expression analysis by western blots appears to be the weak spot of life science, because these blots are so often reported to be manipulated. However, this is only because anybody, even without any background in biology can spot re-used western blot bands, just using a good eye or some computer skills. Unlike with other analytical tools, like real-time PCR or microscopy imaging, you don’t need specialist knowledge or access to raw data to spot digital manipulations of western blots. One of the most famous western blot breeders is the Brazilian diabetes researcher Mario Saad (see whistleblower reports on my site here and here). Below is the case of his two colleagues from Poland.

Some time ago, I was contacted by a Polish scientist with a dossier of suspected western blot duplications in the publication of the pharmacologist Bożena Gabryel from the Department of Pharmacology at the Medical University of Silesia in Katowice, Poland. Gabryel specializes in oxidative stress research, four of her publications on this topic were accused to feature duplicated western blots, in different context. Sometimes suspicions were raised that selected individual bands in different western blots look too similar, which might suggest manipulative band duplications.

Soon after, another whistleblower independently contacted me with another dossier about yet another set of Gabryel’s papers, all featuring as lead or even corresponding author Krzysztof Łabuzek, who is an adjunct professor at this same Medical University  of Silesia with interest in immune system and who also has a clinical practice for internal medicine in a small town near Katowice. Labuzek’s papers seem to feature a whole gallery of re-used western blots, as the dossier suggests. Additionally, that second whistleblower expressed concerns about  western blot splicing and suspected band re-used in papers featuring the first author Joanna Ślusarczyk, PhD student in the lab of Agnieszka Basta-Kaim at the Polish Academy of Sciences in Krakow. Basta-Kaim is also co-author on one Gabryel paper now suspected of data manipulations.

Continue reading “The western blot doctors of Silesia”

Macchiarini and his Russian megagrant

Macchiarini and his Russian megagrant

Below I am publishing the most recent dossier authored by the four whistle-blowers from the Karolinska Institutet (KI) in Sweden: Oscar SimonsonKarl-Henrik Grinnemo, Matthias Corbascio and Thomas Fux. Two of their earlier notifications of research misconduct to KI by their former colleague Paolo Macchiarini are available in full on my site, here and here.

This time it is about Macchiarini’s trachea transplants in Russia, and the so-called Megagrant funding he received from the Russian government for his work at the Kuban State Medical University in Krasnodar. The accusation goes that the KI star surgeon misrepresented the true outcomes of his two first disastrous human experiments with a plastic trachea, performed at KI on the patients Andemariam Beyene and Chris Lyles, both of who died. Also, the whistle-blowers criticise that KI failed to investigate these failed transplants and patient deaths and did not report those to the Russian authorities, which might have helped avoid the unnecessary deaths of at least two Russian patients, Yulia Tuulik and Alexander Zozulya. Continue reading “Macchiarini and his Russian megagrant”

Bavarian court sentences me to prison if I dare repeat unwelcome facts of Walles’ trachea transplants

Just before the end of the year 2016, I received per mail an official letter from the Bavarian Regional Court in Würzburg, where I was found guilty of lies and libel in a trial I was not invited to. Under the threat of a prison sentence of 6 months (since I could never pay even a fraction of the fine of €250,000) I was ordered by the judge to remove a short paragraph from this article which described the same tracheal transplants which the Würzburg University professors Heike and Thorsten Walles were proudly promoting through all available media only a couple of years ago. Now, when the trachea transplant scandal around their former collaborator Paolo Macchiarini exploded, the mere reference to their earlier common publications amounts to a crime of libel in the German state of Bavaria. I was also sentenced to pay the court costs, though I only learned about this Kafkaesque “Prozeß” once a final decision against me was delivered by mail. Luckily, I still have the right to appeal, which I will do once I recruit a suitable legal counsel. If you wish to help in any way, please get in touch. Continue reading “Bavarian court sentences me to prison if I dare repeat unwelcome facts of Walles’ trachea transplants”

Yuletide greetings from Jungebluth’s lawyer

Yuletide greetings from Jungebluth’s lawyer

On December 22nd, I received some Christmas mail. It was a letter from a famous media lawyer, Prof. Dr. Jan Hegemann, recruited by Philipp Jungebluth to deal with my unwelcome reporting. This is the third time a German clinician set lawyers upon me (here and here are the previous two), and the second time it is about  trachea transplants. This lawyer, whose offices are at Potsdamer Platz at the business heart of Berlin and who represented the biggest stars of German media landscape, is certainly not cheap.

Jungebluth was the closest assistant of the scandal surgeon of Paolo Macchiarini, many of their trachea transplant patients have died. Through his lawyer, Jungebluth (who is an unfinished surgeon) denied any responsibility for any of these operations, insisting against a huge mountain of evidence that he was solely contributing academically, as a scientist. The lawyer also insists that Jungebluth’s medical dissertation, completed under Macchiarini’s supervision at the Medical University Hannover (MHH) in Germany, was equivalent to a PhD degree and that his employer Karolinska Institutet (KI) officially recognized this (for some reason, same lawyer apparently deems my own PhD degree as null and void). Interestingly, the lawyer did not deny my earlier report that his client’s dissertation is being investigated by the MHH right now, which may result in the revocation of Jungebluth’s medical doctorate and of all its alleged equivalences.

The lawyer’s main assertion is that his client quit his job at the University Clinic Heidelberg utterly voluntarily, thus abandoning all his research and training as thorax surgeon, to become a junior doctor at some provincial communal hospital near Hannover. Yet the loss of his job in research was what Jungebluth actually profusely lamented just now in an interview with Swedish newspaper.

Continue reading “Yuletide greetings from Jungebluth’s lawyer”

Birchall’s trachea transplant trial at UCL suspended by health authorities

Birchall’s trachea transplant trial at UCL suspended by health authorities

The British laryngologist and UCL professor Martin Birchall is in trouble now, despite all his constant attempts to turn claims into facts and declare the “stem cell”-based cadaveric trachea transplant technology (which he initially developed together with Paolo Macchiarini) a full success. Birchall’s own little trachea transplant trial INSPIRE (see background here), where the method was about to be applied once again, and on four patients outside of any life-threatening conditions, has been now suspended indefinitely by the NHS Health Research Authority and its South Central – Oxford A Research Ethics Committee (REC), as I report exclusively below. Meanwhile, the Information Commissioner’s Office (ICO) is investigating Birchall’s employer UCL Hospital for providing me with inappropriate and misleading information about that trial under Freedom of Information Act (see email here). Also, the Human Tissue Authority (HTA) is investigating a suspected loss of laboratory documentation at the veterinary department of Bristol University, where their former professor, his Bristol colleagues and Macchiarini’s student Philipp Jungebluth generated in 2008 a trachea transplant for Macchiarini’s patient Claudia Castillo in Barcelona (for background, see my report here). Continue reading “Birchall’s trachea transplant trial at UCL suspended by health authorities”

Macchiarini, Jungebluth guilty of research fraud, KI demands retraction of Nature Communications paper

Macchiarini, Jungebluth guilty of research fraud, KI demands retraction of Nature Communications paper

The scandal surgeon Paolo Macchiarini, now professor at Federal University of Kazan in Russia, is preparing to experiment on monkeys using plastic oesophagus. He proclaims previous success in rats, yet today’s decision of his former employer, the Karolinska Institutet (KI) in Stockholm declared that very paper as fraudulent and found Macchiarini and his acolyte Philipp Jungebluth guilty of research misconduct. An earlier decision of the Swedish Central Ethical Review Board (CEPN, read decision here) came on September 6th 2016 to a similar conclusion, with one minor difference. Back then, all senior authors were found “guilty of scientific misconduct”, thus also including Macchiarini’s American collaborator Doris Taylor (who in 2014 almost made him a professor at her University of Texas). Now, all authors except of Macchiarini and Jungebluth have been virtually absolved, while the junior co-authors, the graduate student Sebastian Sjöqvist and the assistant professor Mei Ling Lim received an admonition.

KI now demands the retraction of this 2014 Nature Communications paper:

Sebastian Sjöqvist, Philipp Jungebluth, Mei Ling Lim, Johannes C. Haag, Ylva Gustafsson, Greg Lemon, Silvia Baiguera, Miguel Angel Burguillos, Costantino Del Gaudio, Antonio Beltrán Rodríguez, Alexander Sotnichenko, Karolina Kublickiene, Henrik Ullman, Heike Kielstein, Peter Damberg, Alessandra Bianco, Rainer Heuchel, Ying Zhao, Domenico Ribatti, Cristián Ibarra, Bertrand Joseph, Doris A. Taylor & Paolo Macchiarini

Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats Continue reading “Macchiarini, Jungebluth guilty of research fraud, KI demands retraction of Nature Communications paper”