Things are happening at the French state’s network of research institutes, Centre National de la Recherche Scientifique (CNRS). Their interim president, Anne Peyroche, was now removed prematurely from her position due to evidence of data manipulations in her papers on PubPeer, which I helped uncover. As all credit goes to PubPeer (run chiefly by two CNRS researchers), the announcement unfortunately makes no reference to my call for a minor revolution at CNRS, where these data manipulations were presented to wider public. The official letter which I obtained, is below, both in English translation and its French original.
Selon des journalistes Anne Peyroche serait mise en procédure de mise a pied par le CEA pour fraude et serait en dépression expliquant son "empechement". Mais le CEA n a pas confirmé/infirmé. Sur pubmed AP explique que le mauvais matos du CEA est en cause
Another problematic CNRS chief scientist, Catherine Jessus, who as director of l’Institut des sciences biologiques (INSB) is the head biologist at CNRS, was acquitted in November 2017 by a secret investigation at l’Université Pierre et Marie Curie (UPMC) despite all that long list of suspected data manipulations found in her papers (which I originally presented in this article). As Peyroche faces disciplinary investigation by her employer, the Commissariat à l’énergie atomique et aux énergies alternatives (CEA), nothing of that kind seems to threaten Jessus. Instead, those CNRS researchers who dare to protest against her research integrity shortcomings are being threatened and terrorized, by a furious Jessus herself and her supporters at the top of CNRS.
Catherine Jessus explains to CNRS units directors that she has been cleared from misconduct by Paris 6 university pic.twitter.com/cxDb2kBIyE
Finally, a particularly data manipulations-ridden Institut de Biologie Moléculaire des Plantes (IBMP) in Strasbourg, former home of the legendary Olivier Voinnet (whom Jessus once investigated for doing those same naughty things she might have just a sbadly engaged herself in) has issued a Code for Ethics and Responsible research, which warns potential perpetrators:
IBMP defines scientific misconduct as:
The selective manipulation, fabrication or falsification of scientific data.
When I first started digging into the affair of data manipulations around the former star of plant sciences Olivier Voinnet in early 2015, I was sure to be dealing with a singular case of fraud in French science, which went totally unnoticed for decades. When 2 years later I wrote “a fish stinks from the head down” in my article about Voinnet’s former Strasbourg plant sciences institute and its problematic director, I did not know how far up to the very top this data manipulation scandal will go. Now, it looks like the entire leadership of the Centre National de la Recherche Scientifique (CNRS), French state’s own network of research institutes, might be corrupted and rotten. Research and its integrity at this “largest fundamental research organization in Europe” are overseen by the very people whose own publications should be under investigation for suspected misconduct. A minor revolution is in order in French science, for which I would like to make a case here.
The new interim president of the entire CNRS of 32,000 research employees with the annual budget of €3.2 Billion, Anne Peyroche, has seen now her own publications flagged on PubPeer for data irregularities. In fact, PubPeer itself, which is run by two CNRS employees, seems to be in a pickle. They now vigorously police and delete attempts of criticisms of Peyroche papers. Is the whistleblowing site fighting for its survival, afraid that CNRS might impose its demise any time? How far is the CNRS’ leadership prepared to go, now that their power is threatened by the evidence of misconduct in their own papers?
Catherine Jessus, being the director of its l’Institut des sciences biologiques (INSB) basically the head biologist at CNRS, already reacted to a stream of evidence against her publications on my site and on PubPeer. No, she is apparently not going to check lab books or provide for original data. Instead she declared to her colleagues that CNRS will soon start a massive legal action against yours truly. If true, the State of France announced to soon set its power and resources upon a German blogger, yet the French media refuses to report anything until CNRS issues an official statement in this regard. This information I have from direct sources.
The French scientific society CNRS, a huge country-wide network of research institutes and one of the most influential science institutions in Europe, had enough of me and my reporting. They now blocked me on Twitter, so I don’t spoil their celebration of a book by their senior director and chief of research integrity, Catherine Jessus. The book is titled “Étonnant vivant”, which translated roughly means “Amazing ways to improve your Life science publications with just a little bit of photoshop”. I previously reported about some examples of this art in Jessus publications, which CNRS did not really appreciate.
And of course CNRS did not take it lightly when my past reporting forced them to deal with the Olivier Voinnet affair, whose investigator was Jessus. Neither did they like my writings about another misconduct scandal she had very successfully kept under wraps, that around the former Voinnet postdoc Charles-Henri Lecellier, now CNRS group leader in Montpellier. What finally took the biscuit was my constant leaking of misconduct evidence and of internal information from the former Voinnet institute in Strasbourg, Institut de Biologie Moléculaire des Plantes (IBMP), or as I keep proposing to rebrand it, The Olivier Voinnet Institute for Research Integrity in Plant Sciences. CNRS initially tried it nicely, by sending the IBMP deputy director Jean-Luc Evrard to call me “baby”, then “idiot”, while instructing all other institute employees never to communicate with me, and eventually CNRS simply blocked me on Twitter.
More suspected data manipulations in the papers by the French elite biologists. It was funny enough when the director and several lead figures at the Strasbourg CNRS institute for plant sciences IBMP, former home of the master data manipulator Olivier Voinnet, and even the institute’s evaluators, were found to sport quite a lot of shifty-looking data in their papers. This time, the irony is just too much. Catherine Jessus, developmental biologist specialising on cell cycle research on oocytes and director of CNRS l’Institut des sciences biologiques (INSB) was in charge of two misconduct cases, and now the data integrity of her own papers is called in question. One investigation led by Jessus was about, whom else, Voinnet and his IBMP sidekick Patrice Dunoyer. In summer 2015, Voinnet was barred from CNRS for 2 years (which sounds worse than it is, because his professorship at ETH Zürich in Switzerland remained untouched, read here), and Dunoyer was suspended for one entire month. Jessus’ secret investigation ended with no documents whatsoever but a terse press release made available to outsiders. Both Voinnet and Dunoyer are by now back to publishing papers in prestigious journals.
Jessus was also in charge of dealing with the misconduct evidence against Voinnet’s former postdoc Charles-Henri Lecellier, whom the mighty plant scientist (according to my sources) banned from his Strasbourg lab because he did not trust his research results. It seems Lecellier started to fudge data already during his PhD at CNRS Hôpital Saint-Louis in Paris (PubPeer record here). Imagine how bad it must get that Voinnet expels you for data manipulation! The tenured CNRS researcher was hence moved out of Voinnet’s sight, to work as group leader at the Institut de Génétique Moléculaire de Montpellier, where he continued his own line of data rigging, helped by his trusted friend from IBMP, Guillaume Vetter (see my earlier reporting for a German magazine here and here). Apparently, with full protection from CNRS: in 2013 Jessus actively opposed on behalf of CNRS the impending retraction of a Lecellier co-authored paper, despite earlier misconduct findings against his partner Vetter at the University of Luxembourg (evidence here, especially this letter, example of data manipulations here).
The Olivier Voinnet scandal of almost two decades-long research misconduct and data manipulations has reached its logical conclusion. The French plant pathogen researcher, and everyone who helped him manipulating and publishing dishonest (and occasionally retracted) papers was either forgiven or declared as fully reformed. The siRNA-co-discoverer Voinnet who, cynically put, was too big to fail, remained professor at ETH Zürich and kept his ERC funding. He is meanwhile back to publishing in exactly the same elite journals where he had to retract and correct papers for manipulations. Of all his “partners-in-crime”, only his dependent right-hand man (or sidekick) Patrice Dunoyerwas ever investigated, and as punishment suspended for an entire month by his French employer CNRS. His lab was about to be dissolved, but the Nature Publishing Group came to rescue and accepted his paper (Incarbone et al 2017) just in the nick of time (it’s not even Dunoyer’s only recent publishing success, another one is Montavon et al 2017 in Nucleic Acids Research). The accompanying editorial in Nature Plants, written by the chief editor Chris Surridge can only be described as bizarre, and is titled: “Giving research a sporting chance“. Surridge, who apparently sees data manipulation as a professional sports in race with doping detectives, wrote:
“Dunoyer has been a long-time colleague and collaborator of Olivier Voinnert, and recently a number of their studies, three with Dunoyer as first author, have been retracted while a number more have had formal corrections published to address problems with presented data. However, these instances were investigated by the CNRS and Dunoyer served a temporary suspension as a result. We therefore treated the study we received as we would any other. It was accepted following two rounds of review, during which it was seen by four reviewers. The published paper contains substantial supplementary information (SI). Along with 10 additional figures, there are a further 12 pages presenting the raw data from which the presented figures have been assembled”.
Roland Lill is the quiet star of German molecular biology. The 63-year old professor works at the University of Marburg, on mitochondria, using yeast as a model organism. Lill is also since 2014 member of the Senate at the German Research Foundation (DFG), re-elected just recently, where he represents the interests of German molecular biologists and decides on federal funding distribution and research policies. Since 2016, the Marburg professor is also Senator for Biochemistry and Biophysics at the Leopoldina, which is the German Academy of Sciences. Furthermore, Lill is EMBO member since 2013 and he also used to be Fellow of the Max Planck Society.
Lill’s research focus is on iron-sulfur biogenesis, and his achievements for German science are indeed strong as iron, as evident by his awards and medals (including the Leibniz Prize of €1.55 Mn in 2003), his impressive funding acquisition success and publication record. Recently however, a sulfuric smell of rotten eggs emitted from the whistleblowing platform PubPeer, tainting his legacy. Currently 9 Lill papers are affected, the evidence looks worrisome, and might indicate possible data manipulations. Mostly it is about apparently duplicated gel bands. Luckily however, most papers are 13 and more years old, nobody would expect Professor Lill to have stored the original data for so long, even if it was ever available. The despicable attack on Professor’s Lill research record will be surely thwarted by the journals’ reluctance of dealing with problems in old papers, and of course by the tremendous respect and influence this Senator enjoys in German academia. In fact, both DFG and the two research integrity Ombudspersons of the University of Marburg refused to comment on the PubPeer evidence. Leopoldina announced to me to have the “accusations” addressed by their Ombudsman; DFG mentioned to have had the PubPeer information “forwarded inside the house”.
There is a popular saying: “A fish stinks from the head down”. This is what the situation starts to look like for French CNRS Institut de Biologie Moléculaire des Plantes (IBMP) in Strasbourg, also unofficially known as “The Olivier Voinnet Institute for Research Integrity in Plant Sciences”, after its most famous former research director. A publication from the lab of the institute’s head, Laurence Maréchal-Drouard, seems to contain evidence of inappropriate data manipulation. The gel shown in Figure 1A of Salinas et al 2014, seems to have “no less than 4 copies of a background patch”, according to a concerned reader who contacted me with this evidence. Drouard herself did not reply to my email, possibly because she and her entire CNRS institute are banned from communicating with me.