Roland Lill is the quiet star of German molecular biology. The 63-year old professor works at the University of Marburg, on mitochondria, using yeast as a model organism. Lill is also since 2014 member of the Senate at the German Research Foundation (DFG), re-elected just recently, where he represents the interests of German molecular biologists and decides on federal funding distribution and research policies. Since 2016, the Marburg professor is also Senator for Biochemistry and Biophysics at the Leopoldina, which is the German Academy of Sciences. Furthermore, Lill is EMBO member since 2013 and he also used to be Fellow of the Max Planck Society.
Lill’s research focus is on iron-sulfur biogenesis, and his achievements for German science are indeed strong as iron, as evident by his awards and medals (including the Leibniz Prize of €1.55 Mn in 2003), his impressive funding acquisition success and publication record. Recently however, a sulfuric smell of rotten eggs emitted from the whistleblowing platform PubPeer, tainting his legacy. Currently 9 Lill papers are affected, the evidence looks worrisome, and might indicate possible data manipulations. Mostly it is about apparently duplicated gel bands. Luckily however, most papers are 13 and more years old, nobody would expect Professor Lill to have stored the original data for so long, even if it was ever available. The despicable attack on Professor’s Lill research record will be surely thwarted by the journals’ reluctance of dealing with problems in old papers, and of course by the tremendous respect and influence this Senator enjoys in German academia. In fact, both DFG and the two research integrity Ombudspersons of the University of Marburg refused to comment on the PubPeer evidence. Leopoldina announced to me to have the “accusations” addressed by their Ombudsman; DFG mentioned to have had the PubPeer information “forwarded inside the house”.
Continue reading “Data integrity conspiracy against German research senator Roland Lill?”
The court trial against me by German trachea transplanters Heike and Thorsten Walles ended with the settlement in the appeal court in Bamberg. A costly one, which I had to accept, giving the danger of seeing me and my family driven to bankruptcy before the next very costly court instance can even be invoked for my defence, what with the two impending court fines for the alleged breach of the injunction Walles passed against me with the help of a certain evidence-allergic judge in Würzburg. My legal costs tally up to at least €12,000 and I am now stuck with those. On the plus side, none of my own and my generous donors’ money goes to Walles, they have to pay their own lawyers and half of the court fees, which made them very fuming and livid indeed, as their behaviour in the court room showcased. There the married trachea transplanters also made clear that they saw the operation on their 3 patients (described here and here) as successful research. This Walles stance is unblemished by the undisputed fact that their patients received no actual health benefits from those pig-intestine-based tracheal grafts whatsoever, in fact it looks quite the opposite. Thing is, those 3 operations were all performed in 2003, 2007 and 2009 as compassionate use, without any previous animal experiments, appropriate safety tests or in fact any ethics approvals. A question rises if, or rather how far Walles breached the Nuremberg Code of 1947 and the German medicinal product law, which forbid exactly that kind of research on patients. Continue reading “Walles court trial against me ends with “amicable settlement””
The German trachea transplanters Heike and Thorsten Walles treated the 3 patients with their pig-intestine-based tracheal transplants (one of them performed with Paolo Macchiarini). They are currently suing me in court for reporting about those, while their employer, the University of Würzburg, investigates these tracheal transplants together with the evidence for blatant data manipulations in several Walles publications on suspicion of misconduct. None of those 3 patients is alive today, yet Walles insist that neither of their transplant operations was in any way related to the patients deaths or that it might have reduced their quality of life. They keep declaring those operations as resounding successes, free from any evidence, though the last transplant was performed in 2009 and never again. A corresponding clinical trial, financed by the German Ministry of Education and Research with €1.5 Million between 2009 and 2015 (and briefly mentioned at the beginning of the PEI letter), did not achieve even a single milestone. Not even animal experiments were permitted by the responsible watchdog institution, the Paul Ehrlich Institute (PEI). For almost 7 months, PEI refused to answer my Freedom of Information inquiry. It seems however, my complaints to authorities and the Federal Ministry of Health, finally had an effect.
Continue reading “Paul-Ehrlich Institute admits to have approved Walles tracheal transplant over phone, without questions”
A major misconduct finding hits German life sciences. Karl Lenhard Rudolph, stem cell and ageing researcher, director of the Fritz-Lippmann-Institute (FLI) of the Leibniz Society, was found guilty of research misconduct by an investigation of the Leibniz Society, in a decision published on June 15th. 11 papers in total were investigated, going back as far as 2001. One paper is to be retracted, seven Errata were requested. The investigation confirmed duplications of image parts, inappropriate splicing, rigged loading controls etc. No original data or lab books were available.
Just in Mai 2016, Rudolph’s FLI was raided by the police “on suspected breaches of the animal welfare and drug law, as well as embezzlement” . All animal experimenting was stopped till present day, according to Radio Jena, other sources quoted Rudolph in May 2017 that mouse experiments were approved again, though the police investigation continued. Rudolph also admitted that his own lab was also part of the problem and that 13,000 mice were killed unnecessarily. Was Leibniz Society’s recent tough and public disciplinary action upon FLI director Rudolph the consequence?
The translated report on Rudolph’s research misconduct (my own version) is published below, the German original is here. I have not yet determined which publications from Rudolph lab were investigated, but 5 Rudolph papers were previously flagged on PubPeer. His institute, located in the Eastern German town of Jena, is now banned from Leibniz funding for 3 years, FLI now must report back to the Leibniz Executive Board until November 1st 2017 on the improvements regarding data documentation, quality control as well as tutoring and supervision of employees. Continue reading “German Leibniz institute director Karl Lenhard Rudolph guilty of misconduct”
The court litigation of the German trachea transplanters Heike and Thorsten Walles against me and my reporting has moved into the appeal stage. The appeal hearing will be on July 3rd 2017 in the Bavarian Higher State Court (Oberlandesgericht) in Bamberg. At the same time, the Walles case turns into an institutional conspiracy farce straight of a bad spy novel, which seems to go up to the very top, including the German government.
The central German watchdog on regenerative medicine, the Paul Ehrlich Institute (PEI), keeps breaking German federal law on Freedom of Information (FOI, Informationsfreiheitsgesetz) by refusing to comment on the legality of the 3 tracheal transplants Walles performed (one of them with Paolo Macchiarini). The FOI oversight authority (Bundesbeauftragter für Informationsfreiheit) failed despite several attempts to get PEI to adhere to this federal law and gave up, after admitting to me to lack any means to enforce it. My repeated complaints to the German Federal Ministry of Health, under whose roof PEI operates, did not even achieve an acknowledgement of receipt.
Meanwhile, their current employer, the University of Würzburg, has widened its misconduct investigations against Walles, to collaborate with their past employer, the Hannover Medical School (MHH) and the hospital where two tracheal transplants were performed by Thorsten Walles, the Clinic Schillerhöhe in Stuttgart. It is another question how collaborative or in fact keen on investigating anything at all these two institutions will be. The Stuttgart hospital decided to transplant two patients in 2007 and 2009 with Walles-made pig-intestine-based tracheal grafts in absence of own internal ethics review board and without procuring an ethics vote from an appropriate external institution (instead, they approached an inappropriate one, were sent away, and published this refusal of ethics opinion as an ethics approval).
The medical university MHH on the other hand seems to have no clue what medical ethics are. Just recently, they declared the MD dissertation of Macchiarini’s student Philipp Jungebluth to be utterly unproblematic and refused to investigate it. In light of this and a previous incident (see below), it appears MHH sees foreign patients abroad to be equivalent to research animals.
Even more significant about the widening of the Würzburg investigation is namely who apparently decided not to participate in it.
Continue reading “Walles misconduct investigation in Würzburg widens inside a federal cover-up; Jungebluth’s dissertation whitewashed in Hannover”
Today I stood my second injunction trial (previous here), and once again, the evidence was irrelevant. Today’s trial of Philipp Jungebluth against myself in the Berlin regional court was set for 30 minutes and this is also how long it took. The reason: the judge (and two co-judges) already made up their decision to uphold Jungebluth’s injunction against me (see story here and here), regardless of all evidence from my side about this doctor’s past. They were perfectly free to do so, because it was a speed trial, where (in theory) I was supposed to get my chance to finally defend myself after the very same judge passed that injunction without my prior knowledge or involvement, based on the claims submitted by Jungebluth. Such is the German law on press freedom, take it or leave the country. Also now, I didn’t get to say much, while Jungebluth and his lawyer were welcomed to explain their case to the court once again. My lawyer and I hardly got a chance to squeeze a word in. Continue reading “Judge in Jungebluth trial announces to uphold his injunction, dismisses all evidence”
On March 16th I stood a court trial by the trachea transplanters and University of Würzburg professors Heike and Thorsten Walles against myself. The judge (it was the same who passed the injunction against me) will announce his decision on April 6th, just as I will stand trial in Berlin against their trachea transplant colleague Philipp Jungebluth (see this report). I publish here an extended memory-based protocol which I first published on Facebook. Meanwhile, several large institutions built a protective wall of silence around Walles and their tracheal transplants. The German Medical Association refused investigation in a bizarre letter which I also publish below.
The court hearing
It was the so-called speed trial, so instead of examining evidence, everyone was free to tell the judge their views. Mostly, Walles and their lawyer spoke, occasionally, my lawyer and I were able to squeeze a word in to reject the outlandish or false claims. For example, while her lawyer insisted the tracheal transplants were full success despite dead patients, Heike Walles challenged me to compare her transplants with the first heart transplant which failed. I pointed out that this is exactly the same argument Paolo Macchiarini uses to defend his own failed trachea transplants (for example, here). Continue reading “Will words or actual evidence count in the Walles case?”