s we learned it from the Swedish documentary „Experimenten“, the scandal trachea surgeon Paolo Macchiarini didn’t much like to operate on sick cancer patients: they died too quickly after receiving a trachea transplant. This is why Macchiarini was said to have moved on to patients outside of any life-threatening conditions, like the Russian car accident victim Yulia Tuulik. She died because of the plastic trachea which Macchiarini implanted into her. Yesim Cetir, young victim of a botched operation, was slightly luckier to survive the plastic trachea, but only because it was removed and because of constant emergency care and multiple organ transplants (she is presently in very grave state). However, it seems that even Macchiarini’s cancer patients could have led a relatively long life, had they not agreed to receive his trachea transplants. And I am not speaking about the lethal plastic ones. In fact, the “biological” grafts made of decellurised dead donor tracheas were not such a great success either, and seem to have brought suffering and have shortened lives instead of prolonging them. The British UCL and its hospital UCLH are preparing their own clinical trial with cadaveric tracheas, while busily covering up their role in the Macchiarini scandal.
The trachea transplant doctor and acolyte of Paolo Macchiarini, Philipp Jungebluth, followed up on his previous legal threat to me and used his star lawyer to issue an injunction against me by a court in Berlin. The plaintiffs even declared to have started their legal action following a similar move against me by other former collaborators of the scandal surgeon Paolo Macchiarini, Heike and Thorsten Walles. Here, however, Macchiarini and Jungebluth are proclaimed being “renowned in Germany and world-wide”, no, not how you know them from the more recent Swedish and also British media. Jungebluth is portrayed as an excellent, most-sought for, doctor and top scientist whose only career dent came from what I wrote about him on my site. Once again, I was not invited or informed of the trial, and sentenced never again to assume that Jungebluth might have left his research surgeon employment with the University Clinic of Heidelberg in any other way but entirely of his own accord. The usual threat: €250,000 fine or 6 months in prison.
The lawyer didn’t really have to bother claiming any urgency to have this injunction passed, since Jungebluth is happily employed as junior doctor at a small communal hospital outside Braunschweig, in northern Germany. It sufficed to assert that he felt bothered by my reporting after no less than 35 colleagues asked him about it, and the other side of story became immediately irrelevant for now. Once again, German justice created legal facts out of accusations, without allowing the accused to bring any evidence to defend himself. The alleged eminence of Dr. Jungebluth, scientist and physician, made all evidence obsolete. Except that to all those who ever followed the Macchiarini scandal, the young doctor is not as renowned and respected as the court trusted his lawyer. Conveniently though, in Germany this media reporting never really happened. Continue reading “Jungebluth achieves court injunction against me, because he published in The Lancet”
Below I am publishing the most recent dossier authored by the four whistle-blowers from the Karolinska Institutet (KI) in Sweden: Oscar Simonson, Karl-Henrik Grinnemo, Matthias Corbascio and Thomas Fux. Two of their earlier notifications of research misconduct to KI by their former colleague Paolo Macchiarini are available in full on my site, here and here.
This time it is about Macchiarini’s trachea transplants in Russia, and the so-called Megagrant funding he received from the Russian government for his work at the Kuban State Medical University in Krasnodar. The accusation goes that the KI star surgeon misrepresented the true outcomes of his two first disastrous human experiments with a plastic trachea, performed at KI on the patients Andemariam Beyene and Chris Lyles, both of who died. Also, the whistle-blowers criticise that KI failed to investigate these failed transplants and patient deaths and did not report those to the Russian authorities, which might have helped avoid the unnecessary deaths of at least two Russian patients, Yulia Tuulik and Alexander Zozulya. Continue reading “Macchiarini and his Russian megagrant”
On December 22nd, I received some Christmas mail. It was a letter from a famous media lawyer, Prof. Dr. Jan Hegemann, recruited by Philipp Jungebluth to deal with my unwelcome reporting. This is the third time a German clinician set lawyers upon me (here and here are the previous two), and the second time it is about trachea transplants. This lawyer, whose offices are at Potsdamer Platz at the business heart of Berlin and who represented the biggest stars of German media landscape, is certainly not cheap.
Jungebluth was the closest assistant of the scandal surgeon of Paolo Macchiarini, many of their trachea transplant patients have died. Through his lawyer, Jungebluth (who is an unfinished surgeon) denied any responsibility for any of these operations, insisting against a huge mountain of evidence that he was solely contributing academically, as a scientist. The lawyer also insists that Jungebluth’s medical dissertation, completed under Macchiarini’s supervision at the Medical University Hannover (MHH) in Germany, was equivalent to a PhD degree and that his employer Karolinska Institutet (KI) officially recognized this (for some reason, same lawyer apparently deems my own PhD degree as null and void). Interestingly, the lawyer did not deny my earlier report that his client’s dissertation is being investigated by the MHH right now, which may result in the revocation of Jungebluth’s medical doctorate and of all its alleged equivalences.
The lawyer’s main assertion is that his client quit his job at the University Clinic Heidelberg utterly voluntarily, thus abandoning all his research and training as thorax surgeon, to become a junior doctor at some provincial communal hospital near Hannover. Yet the loss of his job in research was what Jungebluth actually profusely lamented just now in an interview with Swedish newspaper.
The scandal surgeon Paolo Macchiarini, now professor at Federal University of Kazan in Russia, is preparing to experiment on monkeys using plastic oesophagus. He proclaims previous success in rats, yet today’s decision of his former employer, the Karolinska Institutet (KI) in Stockholm declared that very paper as fraudulent and found Macchiarini and his acolyte Philipp Jungebluth guilty of research misconduct. An earlier decision of the Swedish Central Ethical Review Board (CEPN, read decision here) came on September 6th 2016 to a similar conclusion, with one minor difference. Back then, all senior authors were found “guilty of scientific misconduct”, thus also including Macchiarini’s American collaborator Doris Taylor (who in 2014 almost made him a professor at her University of Texas). Now, all authors except of Macchiarini and Jungebluth have been virtually absolved, while the junior co-authors, the graduate student Sebastian Sjöqvist and the assistant professor Mei Ling Lim received an admonition.
KI now demands the retraction of this 2014 Nature Communications paper:
Sebastian Sjöqvist, Philipp Jungebluth, Mei Ling Lim, Johannes C. Haag, Ylva Gustafsson, Greg Lemon, Silvia Baiguera, Miguel Angel Burguillos, Costantino Del Gaudio, Antonio Beltrán Rodríguez, Alexander Sotnichenko, Karolina Kublickiene, Henrik Ullman, Heike Kielstein, Peter Damberg, Alessandra Bianco, Rainer Heuchel, Ying Zhao, Domenico Ribatti, Cristián Ibarra, Bertrand Joseph, Doris A. Taylor & Paolo Macchiarini
Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats Continue reading “Macchiarini, Jungebluth guilty of research fraud, KI demands retraction of Nature Communications paper”
This is a guest post by Johan Thyberg, a 1947-born Swedish biologist and a well-known activist against science fraud. His 2009 published book “Scientific Fraud or Legal Scandal?” meticulously narrates several fraud scandals in Swedish science, one of which I referred to when introducing a guest post of another concerned Swedish academic. Until his academic retirement, Thyberg used to be professor for cell and molecular biology at Karolinska Institutet (KI) in Stockholm, the showplace of probably the biggest medicine scandal of recent times, that of the trachea transplant surgeon Paolo Macchiarini. Continue reading “Karolinska in denial, by Johan Thyberg”
This is the story of three tracheal transplants, performed by the husband and wife team Thorsten Walles and Heike Mertsching (now Walles), former collaborators of Paolo Macchiarini. My investigation quickly led to the Walles couple setting their lawyer on me, demanding almost €3000 immediately and up to €100,000 later. Update: 2 weeks later, they had a Bavarian court sentence me behind my back to a €250,000 fine or 6 months prison term, read here. All because of a single short paragraph from this Macchiarini story, which mentioned their earlier activities. None of their current or former employers nor their lawyer chose to share any specific information about the 3 tracheal transplants, and the fate of these 3 patients.
Macchiarini and the Walleses started their tracheal transplant activities at the Hannover Medical School (MHH), under the regenerative medicine enthusiast Axel Haverich. Together, the team implanted in 2003 a tracheal patch into a cancer patient using a piece of pig intestine, and moved their separate ways soon afterwards. Macchiarini went in 2004 to Barcelona, where he had his famous trachea transplant breakthrough in 2008 (see my report here). The Walles couple went in the same year to Stuttgart in southern Germany. The thorax surgeon Thorsten to the Robert Bosch Hospital, Clinic Schillerhöhe, the regenerative medicine-specialising biologist Heike (back then carrying the name of her previous husband, Mertsching) became professor at the Fraunhofer Institute for Interfacial Engineering and Biotechnology (Fraunhofer IGB). There, the husband and wife team transplanted between 2007 and 2009 two more patients with tracheal replacements made from pig intestine. The clinical success and the actual performance of these transplants is unclear, it is also not helpful that authors chose to omit certain key aspects when the two cases were eventually published. Continue reading “Untangling forgotten tracheal transplants of Heike and Thorsten Walles, who set a lawyer upon me”