On 7 April 2010 the Spanish diabetes researcher Margarita Lorenzo died of metastatic melanoma, aged only 51. Two months after her death, Lorenzo’s colleagues submitted a paper to the journal Diabetes. The paper, which studies the mechanisms of obesity and insulin resistance, seems to be full of manipulated western blot data. While Lorenzo was dying of cancer, her colleagues advanced their careers using her reputation, using their own disreputable Photoshop skills.
Before biology became digital, with its -omics and big data, there were mostly gels and microscopy images. The peak of image use in biomedical papers was reached at the turn of the century, those became the golden times of Photoshop-assisted data manipulation. To celebrate that period, I selected an example of the British cancer researcher Paul Workman, President and CEO of the huge Institute of Cancer Research (ICR) in London.