News Research integrity

Cardiff: no misconduct by TCM professor Wen Jiang, report secret

Cardiff university declared their oncology professor and TCM peddler Wen Jiang innocent of any data manipulation. It then issued then a press release accusing me personally of having slandered Jiang with false allegations of misconduct.

Cardiff University is very proud of its collaboration with manufacturer of Traditional Chinese Medicine Yiling Pharmaceuticals, while the money it brings in is largely a private issue between the two business partners. Unfortunately Cardiff’s surgery and tumour biology professor Wen Jiang, Fellow of Royal Society of Medicine, is at the centre of an affair about data manipulation in his papers, and about criticisms of peddling Yiling’s TCM concoction of ginseng, dried fungus, chicken gizzard and crushed cockroach as a Cardiff University-certified cancer cure, all involuntarily sponsored by the Welsh public and charity Cancer Research Wales. This is why the university threw their own damning internal investigative report out of the window, and had three poorly qualified experts declare Jiang innocent of any data manipulation in his cell biology papers. Cardiff University issued then a press release accusing me personally of having slandered Jiang with false allegations of misconduct.

After having mulled another one of my Freedom of Information (FOI) inquiries for a month, this time a request for the investigative report, Cardiff University declared that their whitewashing opus is secret, because:

“the formal investigation has not upheld the allegations of misconduct and to further distribute this report would be an unnecessary invasion of the privacy of the individual involved”.

cardiff-yiling-ceremony-unveiling-plaque
Yiling Pharma’s owner Yiling Wu and Cardiff University’s President Colin Riordan. Source: Cardiff University

Unlike the university claimed in public, I never raised any misconduct accusations against anyone in person, but merely listed the PubPeer evidence, in fact after Cardiff themselves have verified it, but now apparently expect to disappear after their whitewashing verdict. My regular contributor Smut Clyde and myself however dared to poo-poo Yiling’s business model and Jiang’s practice of wrapping Yiling’s patented TCM herbal, fungal and animal cancer remedies in peer-reviewed British papers, in order to peddle those to Chinese and western patients. Now put in our shameful place, we both prostrate and sincerely apologise to Cardiff University, begging the Welsh academic authorities to have mercy on us. Please don’t deal with us as with that Chinese doctor, who ended up in jail for 3 months for criticising quack produce of another TCM Pharma company, or in  fact as Chinese police handled a reporter who quoted from our article on Wen Jiang and Yiling Pharma.

The Cardiff University press release from 19 April 2018 is here again, in full:

Allegations relating to research misconduct – 19/04/2018

In recent months a number of allegations have emerged on social media and blog posts about research conducted by Professor Wen G. Jiang, notably on https://forbetterscience.com/2018/02/14/fried-divine-comedy-featuring-anti-cancer-cockroach-and-phallic-fungus/#more-23091

Some of these allegations, relating to research misconduct, were formally submitted to Cardiff University by an anonymous whistleblower.

Cases of research misconduct are rare at Cardiff University. However, when allegations are made they are considered in accordance with the University’s Procedure for Dealing with Allegations of Misconduct in Academic Research.

The University’s procedure is in line with guidance issued by the UK Research Integrity Office, to which the University subscribes.

The University has conducted a formal investigation into the allegations.

In all it reviewed allegations relating to 19 publications and has not upheld the allegations of misconduct.

Cardiff University reviews the research quality of all its academic staff as part of performance development reviews and ongoing preparations for the next national Research Excellence Framework (REF). Professor Jiang has been assessed by independent review as having research outputs of a standard eligible for submission to the next REF.

Questions have also been raised about the relationship between the Yiling Pharmaceutical Company Limited and Cardiff University

Yiling Pharmaceutical Company is one of China’s high-tech pharmaceutical companies, devoted to research and development, manufacture and marketing of new medicines. Its products are listed in China’s National Formulary and Health Insurance list.

Its research work has focused on the health benefits of the traditional Chinese medicine preparation Yangzheng Xiaoji and on the development and advancement of new treatments for cancer and infectious diseases, with a particular focus on Chinese medicine.

The Cardiff University – Yiling Group Joint Medical Research Centre was established in 2013 through a gift from Yiling Pharmaceutical Company to Cardiff University. This followed a due diligence report, completed in October 2013, which found no issues of concern.

Under the terms of the gift agreement, Yiling Pharmaceutical Company agreed to donate £300,000 over three years (November 2013 to July 2016) to support a number of scientific researchers, known as “Yiling Scholars”,  through provision of a stipend, research and publication costs, to undertake research projects in cancer molecular pathology at Cardiff University.

Yiling Scholars, who were selected by Peking Cancer Hospital and Capital Medical University, were early career medical doctors and scientists. Yiling Pharmaceutical Company did not play any role in scholar selection, nor were any scholars employees of the company. The use of the gift from Yiling Pharmaceutical to Cardiff University was determined by the University, not the company.

Research conducted at Cardiff University under Professor Jiang’s direction has been concerned with understanding the molecular pathological mechanisms of cancer and metastasis. A minority of studies have examined the efficacy of traditional Chinese medicine preparations and potential mechanisms of action.

Why were those bands duplicated in a Jiang paper Bokobza et al 2010? Can Yiling maybe explain, if Cardiff is afraid to? In any case: this is not misconduct, Cardiff scientists now free to do same. Source: PubPeer

Jiang is innocent of any misconduct, and it will remain forever a secret

  • if his evil scheming postdocs did it behind his back (as in case of Cardiff’s own former Dean Paul Morgan), or
  • if the data manipulations were declared good scientific practice (as French CNRS did in a similar case), or
  • if Wen Jiang was determined to have been an uninvolved, honorary author on his own papers (as German DFG once decided), or
  • if data was found indeed manipulated, and the corresponding author Jiang responsible, but that Yiling money, the money, the money…

This is also why Cardiff’s dealing with Yiling Pharma are secret, as per another of my rejected FOI requests to Cardiff University, which is utterly unashamed to advertise for cockroach-flavoured chicken gizzards as cancer-cure, while chickenshittingly afraid to embarrass themselves by publishing their external investigative report. This is despite the fact that Cardiff did release the previous internal report (published on my site), led by their own cell biologist Adrian Harwood, which confirmed most instances of data manipulation in Jiang’s papers,  precisely the instances of gel band duplications as well as inappropriate gel splicing and image reuse.

Another cancer research professor, whose papers the same internal commission found to be tainted by manipulated data, was Robert Nicholson. In his case however, there was no press release, the investigation might be ongoing or concluded with secret result, with its report fed to chickens and cockroaches, whom Cardoff University then used for TCM cancer cure. Cardiff invited these “experts” to fix the Jiang and Nicholson mess: Judge Ray Singh , Pro Vice Chancellor at Reading University Gavin Brooks and Cardiff’s own optometry professor Jeremy Guggenheim. Of this crack team, only the former cardiovascular researcher and now university manager Brooks might have had a vague idea of what a western blot might be, and why the bands therein should not be duplicated.  Or maybe he is just as clueless about protein gels and their integrity as the optometrician Guggenheim and the judge Singh are, on whose expert legal advice the Cardiff University accused yours truly of slandering poor innocent Jiang.

Screenshot-2018-5-22 Shijiazhuang Yiling Pharmaceutical Co ,Ltd

Despite all being a misunderstanding from libellous blogging, Jiang had by now to correct 3 papers of Cardiff origin for manipulated data: Martin et al 2004, Du et al 2013 and Gao et al 2015, while the data intergrity sleuth Clare Francis kept finding new  evidence of manipulated data in his papers, like this here, in Cheng et al FEBS Letters 2013:

wtz04ht

This was the reply from Cardiff University from today, 22 May 2018, where I was denied access to the investigative report on based of which the same university publicly accused me of libel:

“The University considers that to disclosure this information could be unfair to the individual. The disclosure would not be within the reasonable expectations of an employee and it could constitute an unnecessary intrusion into the privacy of the individual involved.  This could fundamentally undermine the employer/employee relationship and expectation of mutual confidentiality between both parties.  The University has a duty of care to ensure that the information which it holds on its employees is dealt with in an appropriate manner.

In coming to this conclusion the University has consulted guidance produced by the Information Commissioner’s Office on the what can be considered personal data, https://ico.org.uk/media/for-organisations/documents/1213/personal-information-section-40-and-regulation-13-foia-and-eir-guidance.pdf . This guidance states that information relating to an internal investigation or disciplinary hearing will carry a strong general expectation of privacy. “This was recognised by the Information Tribunal in the case of Rob Waugh v Information Commissioner and Doncaster College (EA/2008/0038, 29 December 2008) when it said at paragraph 40 that:“…there is a recognised expectation that the internal disciplinary matters of an individual will be private. Even among senior members of staff there would still be a high expectation of privacy between an employee and his employer in respect of disciplinary matters.”

Furthermore, the formal investigation has not upheld the allegations of misconduct and to further distribute this report would be an unnecessary invasion of the privacy of the individual involved”.

The FOI options are not exhausted though. Let’s see where this leads.


Update 5.04.2019.

The Information Commissioner’s Office (ICO), responsible for England and Wales,  rejected my complaint in full. The decision letter is here, here is the key quote:

“In this case, based on the nature of the withheld information, and the representations provided to the Commissioner by the University, the Commissioner is satisfied that the individual would have had a reasonable expectation that the withheld information would be kept confidential and not disclosed into the public domain without their explicit consent.
In light of the nature of the information and the reasonable expectation of the individual, as noted above, the Commissioner is satisfied that disclosure of the withheld information would not only be an intrusion of privacy but could potentially cause unnecessary and unjustified distress to the individual”.

Basically, Wen Jiang’s career would be damaged if the public were to find out how exactly Cardiff University decided that he is merely a victim of my slander. I agree, three cheers with a ginseng cockroach infusion to that!

 


Donate!

If you are interested to support my work, you can leave here a small tip of $5. Or several of small tips, just increase the amount as you like (2x=€10; 5x=€25). Your generous patronage of my journalism will be most appreciated!

€5.00

 

42 comments on “Cardiff: no misconduct by TCM professor Wen Jiang, report secret

  1. Problematic ophthalmology paper ex-Dean Cardiff University Medical School.

    J Immunol February 1, 2007, 178 (3) 1783-1790; DOI: https://doi.org/10.4049/jimmunol.178.3.1783
    CD59, a Complement Regulatory Protein, Controls Choroidal Neovascularization in a Mouse Model of Wet-Type Age-Related Macular Degeneration

    http://www.jimmunol.org/content/178/3/1783/tab-article-info
    AUTHOR INFORMATION
    Nalini S. Bora2,*, Sankaranarayanan Kaliappan*, Purushottam Jha*, Qin Xu*, Baalasubramanian Sivasankar†, Claire L. Harris†, B. Paul Morgan† and Puran S. Bora2,*
    *Department of Ophthalmology, Jones Eye Institute, Pat and Willard Walker Eye Research Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205; and
    †Department of Medical Biochemistry and Immunology, School of Medicine, Cardiff University, Cardiff, United Kingdom.

    https://pubpeer.com/publications/DBC7F65AB14454A871DF72D3AC216D

    Figure 1C.

    See: https://imgur.com/Yxgye5x

    Like

  2. I don’t think Cardiff University gives a toss about the problematic data.

    Science comes a poor third to money and management.
    What it writes about itself is a good sign of what it values: being in a club with other universities with large turnovers.
    https://russellgroup.ac.uk/about/our-universities/cardiff-university/
    “turnover of £482 million”

    “The discoveries of stem cell pioneer and Nobel Prize winner Professor Sir Martin Evans are now being applied in virtually all areas of biomedicine and have been key to establishing Cardiff as a world-leading centre for biomedical research.”

    What a laugh! Martin Evans did most of his work at UCL and the University of Cambridge. He moved to Cardiff in 2009, which was after being awarded the Nobel Prize.

    https://en.wikipedia.org/wiki/Martin_Evans

    Like

  3. How to factor a retraction into a graph where each publication has been given a value of +1?

    Like

    • https://www.cardiff.ac.uk/media/media-statements/allegations-relating-to-research-misconduct-19042018

      “Yiling Pharmaceutical Company is one of China’s high-tech pharmaceutical companies, devoted to research and development, manufacture and marketing of new medicines. Its products are listed in China’s National Formulary and Health Insurance list.

      Its research work has focused on the health benefits of the traditional Chinese medicine preparation Yangzheng Xiaoji and on the development and advancement of new treatments for cancer and infectious diseases, with a particular focus on Chinese medicine.”

      How can Yiling Pharmaceutical Company “be devoted to research and development, manufacture and marketing of new medicines” if “its ts research work has focused on the health benefits of the traditional Chinese medicine preparation Yangzheng Xiaoji”, which has been known for centuries?

      https://www.bbc.co.uk/news/uk-wales-south-east-wales-24304154
      Prof Wen Jiang is already on record at the BBC, 28 September 2013: “Prof Jiang said they found the Chinese medicine has a significant effect on cancer cells”.

      At 22-26 seconds in the 2013 BBC video Prof Wen G Jiang says “it has been shown to be effective in China”.
      50-52 seconds “It comes from 16 herbs”.

      Yangzheng Xiaoji comes from 15 herbs and female cockroach bodies. The euphemistic use of “herb” is almost poetic.

      If all the write and say on record be true are they peddling old rope, or old cockroach bodies?

      Like

  4. Data in Mol Cancer Res. 2008 Oct;6(10):1594-606 from Int J Oncol. 2007 Feb;30(2):521-9 and J Urol. 2007 Sep;178(3 Pt 1):1086-91.

    Mol Cancer Res. 2008 Oct;6(10):1594-606. doi: 10.1158/1541-7786.MCR-08-0171.
    Bone morphogenetic protein-9 induces apoptosis in prostate cancer cells, the role of prostate apoptosis response-4.
    Ye L1, Kynaston H, Jiang WG.
    Author information

    1
    Metastasis Research Group, Department of Surgery, Cardiff University School of Medicine, Cardiff, United Kingdom.

    Like

  5. https://www.bbc.co.uk/news/uk-wales-47205659

    Cardiff University to cut 380 posts after £20m deficit

    “Proposals include new courses in “areas of global challenges that really matter to Wales”, such as data science and environmental science.

    There are also plans for a new School of Literatures, Languages and Creative Practice.”

    Funny if it were not true.

    There is plenty of problematic data for the future courses of “data science” to analyse here.

    There are schools of “Creative Practice” already here.

    Like

  6. At that time, many of us were stunned to see the final results as no misconduct for all the allegations against Wen Jiang @Cardiff. It was specifically hard for those Chinese people who had long lost their hope in Chinese authorities for fighting misconduct. They had been holding hope to witness how a “respectful” British Cardiff would crush the fraudster. Well, it did not happen.

    People wonder whether the money flooding Cardiff from China’s Yiling Pharmaceuticals played a role. Money alone may not be just it. Look at the latest update from China. On Jan 10, China announced its 2019 annual national awards for achievement in Science & Technology. Guess who was among the winners of the First Class (300k RMB to each winning team)? Yeah, you’re right, Yiling Pharmaceuticals, led by Academician Yiling Wu.

    Promoting TCM is key national policy in China and Yiling Pharmaceuticals is leading the national endeavor. So, Yiling Pharmaceuticals cannot be questioned, Yiling’s herbal concoctions must be worshipped, Yiling sponsored studies (if those could even be considered scientific studies) cannot be questioned, Yiling sponsored researchers cannot be convicted for scientific misconducts. Not only Chinese researchers/institutions should abide the rule, Yiling sponsored Cardiff should too.

    Like

  7. Cardiff University’s President Colin Riordan should be ashamed of himself.

    https://retractionwatch.com/2020/04/15/journals-have-retracted-or-flagged-more-than-40-papers-from-china-that-appear-to-have-used-organ-transplants-from-executed-prisoners/

    https://www.amnesty.org/en/latest/news/2019/04/death-penalty-facts-and-figures-2018/ China remained the world’s leading executioner – but the true extent of the use of the death penalty in China is unknown as this data is classified as a state secret; the global figure of at least 690 excludes the thousands of executions believed to have been carried out in China.

    Like

  8. Pingback: mTOR: conclusions not affected? – For Better Science

  9. Pingback: The Cardiff Coronatest – For Better Science

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: