Science journalism by Leonid Schneider, on research integrity and academic publishing in life sciences and biomedicine
With nobody above him, ICR director Paul Workman was seemingly investigating himself, and found two female colleagues guilty of placing fake data into his papers, primarily the ICR emeritus Ann Jackman. One paper was retracted, another received an outrageous correction. The previous ICR CEO, Alan Ashworth, together with his right-hand man Chris Lord, have their own impressive, but hitherto ignored, record on PubPeer.
This is my review of the Russian book “Megagrant”, which tells of Macchiarini’s adventures with the plastic trachea, much of it played out in Russia, funded by a state Megagrant of €4.5mn. Some books are namely only good as court evidence.
In September 2010, trachea transplant surgeon Paolo Macchiarini was basically at the end of his career of fraud and patient abuse, unwanted by everyone. Except by Karolinska Institutet in Sweden, which pushed the recruitment process through in just 3 weeks, despite warnings from colleagues in Florence, Barcelona and Hannover not to employ someone who was basically a lying psychopath. Yet Karolinska leadership was desperate for some positive reviews for Macchiarini. They finally got them from London, from UCL and GOSH.
Russian officials found an ingenious way to cure cancer and to impress their autocratic president Putin: they simply rig statistics.Continue Reading
Videregen, the Liverpool-based company which bought the trachea regeneration patent from UCL, deployed lawyers against the academics Patricia Murray and Raphael Levy, precisely via their employer University of Liverpool. Main issue is the parliamentary submission by Levy and Murray, subject to absolute privilege. Yet Videregen also cites from the confidential notice of suspected research misconduct Murray and Levy submitted in good faith to UCL.
Another one of Paolo Macchiarini’s past trachea transplant patients has died on 9 July 2018. She received from Macchiarini a cadaveric decellurised trachea in December 2010. By 2018, Zhadyra’s situation critically deteriorated, the dying patient was used for another experiment. On June 5th 2018, Zhadyra received in Moscow another trachea transplant. Responsible was same Parshin who performed the first trachea transplant together with Macchiarini.
Paloma was supposed to the second trachea transplant patient of Paolo Macchiarini’s in Barcelona, in summer 2008. The scandal surgeon gave her a fake diagnosis of a lethal tracheal cancer which she never had, and also “accidentally” mislocated her stent during a enforced bronchoscopy. All to coerce his patient to agree to a trachea transpalnt. Paloma had a lucky escape, twice. She namely also encountered Thorsten Walles.
Karolinska Institutet announced its decision on 6 papers by their former professor and surgeon, Paolo Macchiarini. All are to be retracted, 7 scientists were found guilty of research misconduct, including one of the whistleblowers.
In the aftermath of the scandal around Paolo Macchiarini, which left many patients dead, his former employer Karolinska Institutet requested a retraction a paper. The Swiss-German medical publisher Karger and its journal Respiration however categorically refused and ordered KI not “to patronize the readers of the journal ‘Respiration’.” The German Editor-in-Chief had namely a huge conflict of interest.
In 2017, UCL invited an external expert commission to investigate the deadly trachea transplants performed by the former UCL honorary professor Paolo Macchiarini. An already sacked UCL nanotechnology professor, Alexander Seifalian, whose lab made the two UCL plastic POSS-PCU tracheas in 2011, was announced as the main culprit on UCL side. All this despite Seifalian’s having had no clinical role, training or ambitions, as he professed in his interview to the investigative committee, which I now obtained.
