Maria Fousteri, the ERC-funded western blot cheater

Maria Fousteri, the ERC-funded western blot cheater

Maria Fousteri is a highly successful Greek molecular cell biologist who studies the molecular mechanisms of DNA damage repair in human cells and their protective roles “against mental dysfunction or cancer”. Her works in the field of nucleotide exchange repair and epigenetic chromatin remodelling, done at the Leiden University Medical Center (LUMC) in the Netherlands in the department led by the LUMC professor Leon Mullenders, appeared in elite journals such as Molecular Cell.  These publications, described to me by a leading DNA repair researcher as “definitely major papers in the field” consequently helped Fousteri to an ERC starting grant of €1.5 Million for her research project “TransArrest” in 2012. Her young ERC-funded lab is located at the Biomedical Sciences Research Center “Alexander Fleming”in Greece, 20 km south of Athens.

The economic crisis-struck Greek science community should surely be rejoicing about such success of their returning top-scientist, with the most prestigious EU funding award from the ERC in tow. Instead, Fousteri’s colleagues at Alexander Fleming recently learned that a LUMC investigation found her guilty of data manipulations and research misconduct in 5 publications. Once again, it is about western blots. Images were re-used in unrelated context, lanes spliced and occasionally even bands duplicated inside a continuous gel image. The DNA nucleotide exchange repair specialist Fousteri seems to be just as professional in exchanging of western blot bands. These are the five papers, the first four (all in Molecular Cell) were recommended for retraction: Continue reading “Maria Fousteri, the ERC-funded western blot cheater”

False priorities at EU2016NL: Mandate Open Data instead of Gold Open Access!

False priorities at EU2016NL: Mandate Open Data instead of Gold Open Access!

Open Science is these days largely about mandatory publishing in Open Access (OA), regardless of the costs to poorer scientists or the universities which already struggle to pay horrendous subscription fees. Meanwhile, publishers openly declare that the so-called Gold (author-pays) OA will be much more expensive than even current subscription rates, yet wealthy western institutions like the Dutch university network VSNU or the German Max Planck Society do not seem troubled by this at all. They seriously expect the publishing oligopoly of Elsevier, SpringerNature and Wiley to lower the costs for Gold OA later on, out of the goodness of their hearts (as this winter’s invitation-only Berlin12 OA conference suggests).

At the last major Open Science conference in Amsterdam on April 4-5 (EU2016NL) the EU Commissioner for Research, Science and Innovation, Carlos Moedas and EC Director-General for Research and Innovation, Robert-Jan Smits, announced to achieve the flip to Gold OA by 2020. Open Data, on the other hand, is just a buzzword to them.

Below, I will argue that Open Data is much more important than OA, which in turn will be much cheaper and easier to achieve once unconditional sharing of research data is in place. Continue reading “False priorities at EU2016NL: Mandate Open Data instead of Gold Open Access!”