The Kathrin Maedler Dynasty

The Kathrin Maedler Dynasty

German academic jargon has a peculiar expression: Doktorvater. It means “doctoral father”, a fatherly figure who takes his helpless PhD student progeny by the hand and guides and teaches the offspring of his academic loins the wisdom of science, up to the graduation. Nowadays with the system being less patriarchal, one can instead have the figure of a Doktormutter, doctoral mother. Which obviously doesn’t bring same gravitas or inspires same respect and awe, and is therefore hardly ever used.

The German diabetologist and Professor and University of Bremen Kathrin Maedler is a central figure of an academic dynasty. Using Photoshop simulations (read here), she discovered a cure for diabetes via inhibition of the inflammatory cytokine interleukin-1-beta (IL-1β), which was then confirmed as a definite cure for diabetes in clinical trials led by her own Swiss Doktorvater Marc Donath, then professor at University of Zürich, now in Basel. Over 15 years later, the Maedler-Donath cure was proven as utterly ineffective against hypoglycaemia and diabetes by same Donath, in another clinical trial. Because of her Photoshop creativity with discovering diabetes cures and ensuing retractions, Donath’s past PhD student Maedler was asked by the German Research Council DFG to surrender her prestigious Heisenberg professorship, while the German Diabetes Society (DDG) revoked her Ferdinand Bertram Prize from 2011 (read here). Since 2017, her PhD thesis is again under investigation of University of Zürich.

That diabetes research was also what made the career of Maedler’s own PhD student, Amin Ardestani, presently junior research group leader at the University of Bremen. His thesis received an award from the local Rotary Club, of course also Ardestani got a prize from DDG, which he also saw revoked for engaging into same activities as his Doktormutter. Still, he is still receiving awards, including from Elsevier. I will present below some data irregularities and unacknowledged textual reuse from Ardestani’s 2013 PhD thesis, which was supervised by Maedler.

Continue reading “The Kathrin Maedler Dynasty”

Kathrin Maedler loses Heisenberg Professorship, Diabetes award, found guilty of misconduct by DFG

Kathrin Maedler loses Heisenberg Professorship, Diabetes award, found guilty of misconduct by DFG

The German central research funding society DFG has issued a press release about two decisions on research misconduct. The main point concerns the Bremen University diabetes researcher Kathrin Maedler (see my story here) and strips her of the prestigious Heisenberg professorship awarded to her by DFG in 2014, after having found her guilty of misconduct and co-responsible for misrepresentation of research data in 6 publications. Today’s DFG decision stands in contrast to two previous investigations by the Universities of Bremen and Zürich, which acquitted Maedler of all suspicions of misconduct and upheld the validity of all her published research results. This is my Google-translate assisted English translation of the Mädler section of DFG press release.


Scientific misconduct: Decision in two DFG procedures

The General Committee decides to withdraw Heisenberg’s professorship […]

The German Research Foundation (DFG) is once again drawing conclusions from the scientific misconduct by the scientists it funded. In its meeting on 8 December 2016 in Bonn, the main committee of the largest research funding organization and central self-administration organization for science in Germany decided in two cases to implement measures in accordance with the DFG procedural rules for dealing with scientific misconduct. In doing so, it followed the recommendation of the DFG committee to investigate allegations of scientific misconduct. Continue reading “Kathrin Maedler loses Heisenberg Professorship, Diabetes award, found guilty of misconduct by DFG”

Kathrin Maedler: persecuted genius or zombie scientist?

Kathrin Maedler: persecuted genius or zombie scientist?

The prize-winning German pharmacologist and diabetes researcher Kathrin Maedler is regularly in the German and international news, either as a celebrated genius about to cure diabetes or as a potential cheater, responsible for masses of duplicated images in her publications. The rectorate of her own University of Bremen absolved their professor of all suspicions of data manipulations, while admitting image duplications and loss of original data. One argument was that all results were successfully reproduced, yet by whom: that the Bremen rectorate prefers not to answer, together with all other relevant questions which would have made this investigation anywhere credible. In the same vein, another investigation at the University of Zürich in Switzerland, where Maedler did her PhD in 2000-2004 under the supervision of Marc Donath, absolved them both of any suspicion of misconduct as well, while refusing to provide any further explanations. Meanwhile, other labs have refuted Maedler’s discoveries, but these publications were dismissed by the University of Bremen as irrelevant. Maedler also had to retract a publication Ardestani et al 2011 from the Journal of Biological Chemistry (which is known to have a rather tough stance on suspected misconduct). Continue reading “Kathrin Maedler: persecuted genius or zombie scientist?”