Research integrity University Affairs

The minor infractions by Diana and Fathey

"your remarks exceed the bounds of acceptable professional conduct, and we hereby request that you cease such conduct immediately."- Université du Québec à Montréal

Our heroes are Diana Averill-Bates and Fathey Sarhan, two pension-age professors at University of Québec in Montreal (UQAM). The stuff they published is ridiculously bad, and some of that was recently retracted. But their university disagrees, and finds no issues with their research. UQAM leadership ordered me to delete my past reporting of December 2025 Shorts, so of course I just had to write this instead.

Averill is toxicologist and cancer researcher, and New Zealand native. She came to Canada in 1983 as postdoc and became professor at UQAM in 1986, a position she still seems to hold, maybe she is about to retire soon, being around 70 years old. Her faculty colleague Sarhan is a plant scientist, a native Egyptian who came to Canada in 1960ies to study, joined UQAM in 1978 as postdoc and soon rose to full professor. He became emeritus already in 2010, received in 2011 a Gold Medal from the Canadian Society for Plant Physiology, and must be around 80 years old now.

Both have horrendously bad PubPeer records, here is Diana’s, and here is Fathey’s, with a substantial overlap. In December 2025, Elisabeth Bik caused three retractions for these Canadian scholars, with hopefully many more to follow.

Moshe Szyf demands an apology

“We demand that you publicly apologize to our clients and retract all your statements within one week from today. Failure to do so will result in our taking an action in both public and private law, against you and McGill University.” – Moshe Szyf and Michael Meaney, via lawyer

This paper was flagged in May 2025, the first author Francine Hamel used to be Sarhan’s postdoc, while Mélanie Grondin was his PhD student. Francine Denizeau (now Beaudoin-Denizeau) is another UQAM professor, long since retired:

Francine Hamel, Mélanie Grondin, Francine Denizeau, Diana A. Averill-Bates, Fathey Sarhan Wheat extracts as an efficient cryoprotective agent for primary cultures of rat hepatocytes Biotechnology and Bioengineering (2006) doi: 10.1002/bit.20953 

Elisabeth Bik: “Concerns about Figure 3. Boxes of the same shape and color highlight unexpected repetitive features in panels B, C, and D.”

Retracted on 2 December 2025 (highlights mine):

“The retraction has been agreed due to concerns raised by third parties. Specifically, the micrographs presented in Figure 3B, C and D were found to contain numerous repetitive elements (i.e., cells) suggesting inappropriate image processing. Investigation by the publisher has confirmed the validity of the concerns.

The authors were unable to retrieve the raw data underlying Figure 3 due to the time elapsed since original publication. They also stated that the images presented in Figure 3 were acquired as original images and have not been altered in any form. They conducted an independent analysis of the magnified published images, highlighting that the cells identified as duplicated exhibit differences. According to the authors, the observed similarities are characteristic of cells within a homogeneous population (i.e., hepatocytes) and are therefore to be expected, thereby refuting allegations of inappropriate image editing. The authors stated that the issues identified do not affect the conclusions of the article.

However, the editors have deemed the clarification from the authors as insufficient to resolve their concerns. The similarities detected in Figure 3 were found to outweigh the differences highlighted by the authors and were considered unlikely to result solely from morphological resemblance within a homogeneous population of primary isolated hepatocytes. The editors have determined that the new experimental data generated by the authors to replace the images in Figure 3 were unsuitable for direct comparison with the originally published data, due to the substantial time gap between the two experimental sets. Therefore, the concerns of the editors were not addressed acceptably and accordingly, the article must be retracted. The authors disagree with the retraction decision.”

Consider: scientists constantly fail to store data for longer than 5 years, but here some retired but not yet clinically demented professors claim to be perfectly able to preserve reagents and even frozen cell lines for decades and repeat any ancient experiment in a matter of weeks, in order to replace their old fake figures.

Also: that fraudulent liver research paper ended with: “In memory of Moustafa Shereen and Madeleine Gobeille-Labrie, great friends, whose courage in fighting
liver disease inspired us to work in this area of research
.” Wow.

The second retracted paper by the same team (sans Denizeau) is even worse:

Mélanie Grondin , Francine Hamel , Diana A. Averill‐Bates, Fathey Sarhan Wheat proteins improve cryopreservation of rat hepatocytes Biotechnology and Bioengineering (2009) doi: 10.1002/bit.22270 

Elisabeth Bik: “Concerns about Figure 4: First, five of the panels here appear to have been published before […] Other data in this paper also looks similar to that in the Cell Transplantation paper, albeit presented differently.”
See Fig 2 of
Mélanie Grondin , Francine Hamel , Diana A. Averill-Bates, Fathey Sarhan Wheat proteins enhance stability and function of adhesion molecules in cryopreserved hepatocytes Cell transplantation (2009) doi: 10.3727/096368909788237104 

This is the Fig 4 (or Fig 4, depending on the paper):

Elisabeth Bik: “Most importantly, panels in this paper’s Figure 4 – as well as those in Cell Transplantation (2009) Figure 2 – appear to contain duplicated elements.”

The retraction from 2 December 2025 had almost the same wording:

“The retraction has been agreed due to concerns raised by third parties. Specifically, several micrographs presented in Figure 4 were found to contain numerous repetitive elements (i.e., cells) suggesting inappropriate image processing. Furthermore, data presented in Figure 4 and part of the data presented in Figure 1 were found to have been previously published by the same author group [Grondin et al, (2009); https://doi.org/10.3727/096368909788237104]. Investigation by the publisher has confirmed the validity of the concerns.

The authors were unable to retrieve the raw data underlying Figure 4 due to the time elapsed since original publication. They also stated that the images presented in Figure 4 were acquired as original images and have not been altered in any form. They conducted an independent analysis [….]

The editors have determined that the new experimental data generated by the authors to replace the images in Figure 4 were unsuitable […] The authors disagree with the retraction decision.”

Mr ACE2 Josef Penninger, Greatest Scientist of Our Time

As a young Wunderkind, Josef Penninger discovered the ACE2 receptor. Now he invented the cure for the coronavirus which will work in his hands where Big Pharma failed. He was never found guilty of research misconduct and never retracted a paper. Dr Penninger is a Genius making a COVID-19 vaccine.

Here a related paper by these same clown troupe, again about frozen liver cells preserved with wheat extract:

Mélanie Grondin , Francine Hamel , Fathey Sarhan, Diana A. Averill-Bates Metabolic activity of cytochrome p450 isoforms in hepatocytes cryopreserved with wheat protein extract Drug metabolism and disposition (2008) doi: 10.1124/dmd.108.021162 

Elisabeth Bik : “Concern about Figure 1:
Several panels appear to contain repetitive elements.”
“Also compare the ‘Uncoated WPEs’ panel marked above to the WPE panel in Figure 2 of” Grondin et al Cell transplantation (2009)

You might wonder, why so much fraud to convince readers that wheat extract can be used to freeze mammalian cells. Well, Sarhan, Averill, Hamel, Grondin, Denizeau and Denizeau’s first husband Jacques patented this stuff two decades ago! This patent is meanwhile abandoned, probably because Sarhan’s company ICE Biotech Inc was “dissolved for non-compliance” in 2011.

As you can imagine, Averill has much more of that fake stuff on PubPeer, courtesy of Bik’s sleuthing. Here is a third retraction, again in the same Wiley journal, the last author is Sarhan’s former postdoc Francois Ouellet, who is by now full professor at UQAM. Sarhan himself only featured in acknowledgments (“We thank Professor Emeritus Fathey Sarhan, initiator of this research program, for ongoing fruitful discussions regarding cell cryopreservation with plant products.”)

Mélanie Chow‐shi‐yée , Mélanie Grondin , Diana A. Averill‐Bates, François Ouellet Plant protein 2‐Cys peroxiredoxin TaBAS1 alleviates oxidative and nitrosative stresses incurred during cryopreservation of mammalian cells Biotechnology and Bioengineering (2016) doi: 10.1002/bit.25921 

Elisabeth Bik: “Concern about Figure 4A: The TaBAS1 panel in the HEPATOCYTES set appears to contain unexpected repetitive elements. Shown with blue and red boxes.”

This was the retraction from 3 December 2025:

“The retraction has been agreed due to concerns raised by third parties. Specifically, Figure 4A was found to contain repetitive elements (i.e., cells) suggesting inappropriate image processing. Investigation by the publisher has confirmed the validity of the concerns.

The authors were unable to retrieve the raw data underlying Figure 4A due to the time elapsed since original publication. They also stated that the images presented in Figure 4A were acquired as original images and have not been altered in any form. The authors conducted an independent analysis […]”

And so on, you read this insanity already, about “observed similarities […] to be expected” and “new experimental data generated by the authors”.

This was not retracted (yet), again with Sarhan’s former PhD student Grondin:

Sarah Kassis , Mélanie Grondin , Diana A. Averill-Bates Heat shock increases levels of reactive oxygen species, autophagy and apoptosis Biochimica et Biophysica Acta (2021) doi: 10.1016/j.bbamcr.2020.118924 

Elisabeth Bik: “Concern about Figure 2’s Western blot: Red and cyan boxes highlight bands that look unexpectedly similar”
“Concern about Figure 2D: Yellow boxes: […] the same group of three cells is visible twice. Marked only in the LC3 panel but also visible in the other panels.”

After I published those December 2025 Shorts, Averill went to PubPeer to protest. She “enlarged the image” and found out that “There was no duplication of bands” and “no duplication of cells“, and anyway, “These images do not affect the results, interpretation or scientific conclusions of the paper.” If those figures were so irrelevant, why are they in the paper then? Is any data in Averill’s papers relevant to her conclusions?

David Goltzman’s cowardice

“It is cowardly to be anonymous.  […] This is harassment, for whatever benefit you will gain from this. Please cease and desist” – David Goltzman

In case you missed the dashing Denizeau (do appreciate that bizarre photo of her in the lab, from 1981), here she is again with Averill:

Khadidja Haidara , Michel Marion , Marielle Gascon-Barré , Francine Denizeau , Diana A. Averill-Bates Implication of caspases and subcellular compartments in tert-butylhydroperoxide induced apoptosis Toxicology and Applied Pharmacology (2008) doi: 10.1016/j.taap.2008.01.010 

Elisabeth Bik : “Concern about Figure 3C-2:
Boxes of the same color highlight lanes that look unexpectedly similar. One pair is in mirror image”
“Concern about Figure 5C-2:Blue boxes highlight lanes that look unexpectedly similar.”
“Concern about Figure 4C-2: Orange boxes highlight lanes that look unexpectedly similar.”
“Concern about Figure 5A-2: Pink boxes highlight lanes that look unexpectedly similar.”

Denizeau and Averill, what a duo… Bik found that “Several Western blots in this paper appear to contain duplicated lanes”:

Magdalena Jurkiewicz, Diana A Averill-Bates, Michel Marion , Francine Denizeau Involvement of mitochondrial and death receptor pathways in tributyltin-induced apoptosis in rat hepatocytes Biochimica et Biophysica Acta (2004) doi: 10.1016/j.bbamcr.2004.04.001 

Fig 3B
Fig 4C
Fig 4A
Fig 5A

Did anyone every consider the possibility that the highly toxic biocide tributylin can also cause gel band duplication? Again Averill, Denizeau, plus again their UQAM colleague Michel Marion, who died in 2020 aged 67, thus spared the shame:

Mélanie Grondin , Michel Marion , Francine Denizeau , Diana A. Averill-Bates Tributyltin induces apoptotic signaling in hepatocytes through pathways involving the endoplasmic reticulum and mitochondria Toxicology and Applied Pharmacology (2007) doi: 10.1016/j.taap.2007.03.028

Elisabeth Bik: “Concerns about Figure 4: Boxes of the same color highlight several lanes that appear to look similar to each other”

Yet another fake paper, shall we blame Averill’s PhD student here, Ahmed Bettaieb, who made it to associate professor at University of Tennessee in Knoxville, USA? Or the other coauthor?

Ahmed Bettaieb, Diana A. Averill-Bates Thermotolerance induced at a mild temperature of 40°C alleviates heat shock-induced ER stress and apoptosis in HeLa cells Biochimica et Biophysica Acta (2015) doi: 10.1016/j.bbamcr.2014.09.016 

Elisabeth Bik: “Figure 5C.
Yellow boxes: Two panels appear to overlap with each other
Pink boxes: Two other panels appear to overlap with each other”
“Blue boxes: The pIRE1aS724 panel in Figure 6B looks very similar to the Caspase 3 panel in Figure 6C.”
“Red boxes: The cATF6a panel in Figure 2A looks very similar to the CHOP panel in Figure 3B.”
Figure 4C, […] Green boxes: In the GAPDH panel, two lanes appear to be visible twice.”

Also Claire Francis briefly joined the treasure hunt in Averill’s papers, here again her pet topic of curing cancer with heat:

Audrey Glory , Ahmed Bettaieb , Diana A. Averill-Bates Mild thermotolerance induced at 40 °C protects cells against hyperthermia-induced pro-apoptotic changes in Bcl-2 family proteins International journal of hyperthermia (2014) doi: 10.3109/02656736.2014.968641 

Fig 2a
Fig 3a

Also this is an orgy of fake gels, will Averill still have the raw data, after 6 years have passed?

Marceline Tchouagué , Melanie Grondin , Audrey Glory , Diana Averill-Bates Heat shock induces the cellular antioxidant defenses peroxiredoxin, glutathione and glucose 6-phosphate dehydrogenase through Nrf2 Chemico-Biological Interactions (2019) doi: 10.1016/j.cbi.2019.06.030 

Elisabeth Bik : “Concern about Figures 2, 4, 4, and 8: Boxes of the same color highlight lanes that look unexpectedly similar”

Here we have fake blots, fake microscopy, and fake flow cytometry, no wonder Bettaieb is professor now:

Paulina K. Wrzal, Ahmed Bettaieb, Diana A. Averill-Bates Molecular Mechanisms of Apoptosis Activation by Heat Shock in Multidrug-Resistant Chinese Hamster Cells Radiation Research (2008) doi: 10.1667/rr1214.1 

Elisabeth Bik: “Figure 3A […] Orange boxes: Two bands look remarkably similar”
“Concern about Figure 7C, also found by Proofig:
PInk boxes: Two lanes appear to be visible twice, but in mirror image.”
“Figure 14. Red boxes: Panels C3 and D3 appear to look identical Yellow boxes: Panels E3 and E4 appear to look identical”
“Concern about Figure 13:
Green boxes: Two flow cytometry panels are remarkably similar”

Well done, Dr Bettaieb! And of course, well done, Dr Averill:

Julie Roy , Pragathi Pallepati , Ahmed Bettaieb, Diana A. Averill-Bates Acrolein induces apoptosis through the death receptor pathway in A549 lung cells: role of p53 Canadian journal of physiology and pharmacology (2010) doi: 10.1139/y09-134 

Elisabeth Bik: Concern about Figure 8C.
Pink arrows: splice lines appear to be visible between the first and second, and between the fourth and the fifth lane
Green arrows: a horizontal splice line might be visible in the second, third, and fifth lanes.
Yellow boxes: The 85 kDa band in the first lane looks like that in the fifth lane. As noted above, some straight background transition lines appear be visible around the latter.
Blue boxes: The top bands in the second and fifth lane look very similar.”

Well done indeed, that’s how one becomes professor….

Julie Roy , Pragathi Pallepati , Ahmed Bettaieb, André Tanel , Diana A. Averill-Bates Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells Chemico-Biological Interactions (2009) doi: 10.1016/j.cbi.2009.07.001 

Elisabeth Bik: “Concern about Figure 4D:
Red boxes: In the Cytosol Cytochrome c panel, the 7 uM and 14 mM lane bands look remarkably similar.”
“Concern about Figures 1G and 7D: Blue boxes: Two GAPDH panels representing different experiments, look remarkably similar”

Yes, Averill’s students wilfully participated in this fraud. But the main culprit is not them.

Pragathi Pallepati , Diana A. Averill-Bates Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide Free Radical Biology and Medicine (2011) doi: 10.1016/j.freeradbiomed.2010.11.022 

Elisabeth Bik : “Concern about Figure 1B: Cyan boxes: Two panels unexpectedly look similar to each other.”
“All panels also look similar to those in”
Pragathi Pallepati , Diana Averill-Bates Mild thermotolerance induced at 40 degrees C increases antioxidants and protects HeLa cells against mitochondrial apoptosis induced by hydrogen peroxide: Role of p53 Archives of Biochemistry and Biophysics (2010) doi: 10.1016/j.abb.2009.12.014 
“Concerns about Figure 1E and 3C:
Red and blue boxes highlight lanes that look unexpectedly similar”

Same authors, just as fraudulent, and it was corrected by Elsevier:

Pragathi Pallepati , Diana A. Averill-Bates Activation of ER stress and apoptosis by hydrogen peroxide in HeLa cells: Protective role of mild heat preconditioning at 40°C Biochimica et Biophysica Acta (2011) doi: 10.1016/j.bbamcr.2011.07.021

Elisabeth Bik: “Concern about Figure 1A;
Blue boxes highlight two panels that appear to overlap unexpectedly, with a change in magnification.”
“Concern about Figure 11 and 12: Pink boxes highlight two GAPDH panels that represent different samples”
“Concern about Figure 16C: Green boxes highlight two panels that unexpectedly overlap”

The Corrigendum was issued on 12 November 2025 (highlights mine):

“The authors regret that there is similarity between the two photo panels b and f in the published version of Fig. 1A. It is possible that there was an honest copy-paste mistake during sizing and assembly of the photos for the figure. Given that the original data from 2009 to 2010 is not available after this amount of time, the authors have repeated the experiment and are providing revised photos for Fig. 1A to correct the scientific record. The experiment has been repeated at least three times with distinct cell preparations obtained on different days. The data in Fig. 1A represents a control condition, which does not affect or change the interpretation of any of the results, the interpretation and the overall scientific conclusions of the published paper. To address this issue, the authors have provided a new version of Fig. 1A. The authors would like to apologise for any inconvenience caused.”

I think some pathological liar (who might possibly answer to the name of Diana), is ripe for a mental institution. Instead, she went to PubPeer to claim that the gel bands in Figures 11 and 12 and microscopy images In Fig 16 were never identical because she found differences by enlarging them (raw data obviously is unavailable). Averill also added: “The information shown in these images does not affect or change the results, interpretation or scientific conclusions of the data published in this paper.” And worse: Elsevier agreed with her!

All this fraud went unnoticed over many years. Averill started to troll the scientific community by copy-pasting entire figures, next to each other, see Redza-Dutordoir et al 2016, which was corrected in Sepember 2025 to declare that it “does not affect the results, interpretation, or conclusions of the article“. Why waste time with Photoshop when you can publish shameless Frankengels like this one, here with Ouellet:

Mélanie Chow-shi-yée, Melanie Grondin , Francois Ouellet, Diana A. Averill-Bates Control of stress-induced apoptosis by freezing tolerance-associated wheat proteins during cryopreservation of rat hepatocytes Cell Stress and Chaperones (2020) doi: 10.1007/s12192-020-01115-y 

Aneurus inconstans : “I fail to understand how a Western blot like that in Figure 4 (red box) could have been accepted in 2020. Each and all bands are cropped out and assembled together, which makes PARP level quantification (graph above) completely meaningless. Moreover, the bands of GAPDH loading control are far from being similar.”

Sometimes however, the Canadian professor is always ready to fight back with fake “raw data”!

Tatiana Souslova, Diana A. Averill-Bates Multidrug-resistant hela cells overexpressing MRP1 exhibit sensitivity to cell killing by hyperthermia: interactions with etoposide International Journal of Radiation Oncology*Biology*Physics (2004) doi: 10.1016/j.ijrobp.2004.07.686 

Elisabeth Bik: “Concern about Figure 4: Red boxes highlight two lanes that look unexpectedly similar.”

Averill replied on PubPeer with scans of gels:

We sent the original Western blot films for Figure 4, from about 20 years ago, to the journal. The films prove that there was no duplication or splicing of protein bands or unethical manipulation of our published image. The image is attached. The journal viewed the image and closed the case on May 19, 2025

See, suddenly two decades old raw data becomes available! Well, not quite. The “original Western blot films” didn’t match the published material, but the published figure was clearly falsified in Photoshop, as Bik showed:

“The right two lanes in the film look different from each other, while the right two lanes in the published figure 4 look very similar to each other (red boxes).
The marker band appears to have disappeared, while a duplicate area is observed in its place (blue boxes)”

I wrote to Averill, and expressed my concerns about her mental health, but received no reply. Also her colleague, the plant scientist Fathey Sarhan, didn’t reply. I then wrote the December 2025 Shorts with the material above, and sent my article to Averill, Sarhan, and the UQAM leadership.

On 23 December 2025, I received this incredible communication from the Vice-Rector for Research, Creation and Dissemination, Lucie Ménard, who is a professor in linguistics:

“Mr. Schneider,

Further to your recent messages and statements published on your website, we believe that your remarks exceed the bounds of acceptable professional conduct, and we hereby request that you cease such conduct immediately.

The Committee that reviewed Professor Averill’s case conducted a thorough and rigorous examination and concluded that the matter did not constitute fraud. The Committee determined that the breach of research integrity and responsible conduct was minor and found that the identified infractions did not materially affect either the conclusions or the substantive validity of the articles in question.

We therefore request that you correct the factual record accordingly.

Vice-rectorat à la recherche, à la création et à la diffusion

Université du Québec à Montréal”

There are some linguistic points I would like to make. First, Professor Menard may decide what “acceptable professional conduct” at her UQAM is, but she doesn’t get to do this at For Better Science. Second, what the f*** is wrong with those people.

Original photos: UQAM, sciencepresse.qc.ca

All this prompted Aneurus Inconstans to study other papers by these Quebec clowns, and being a plant researcher, the sleuth focussed on Sarhan, who now has a PubPeer record of his own, separate from Averill. For example, with Norman Huner, Canada Research Chair at University of Western Ontario:

Christian NDong , Jean Danyluk, Kenneth E. Wilson , Tessa Pocock , Norman P.A. Huner, Fathey Sarhan Cold-Regulated Cereal Chloroplast Late Embryogenesis Abundant-Like Proteins. Molecular Characterization and Functional Analyses Plant Physiology (2002) doi: 10.1104/pp.001925 

Aneurus inconstans : “Figure 3E: two bands of the Rubisco control have been copied and pasted (red boxes). Conrast enhancement highlights two peculiar dots below the bands (blue arrows).”
Elisabeth Bik: ” Figures 3C and 3D: Green boxes: Three lanes in the top panels of Figure 3C and 3D look much more similar than expected.”

Or how about this, with Sarhan’s former postdocs Ouellet and Mario Houde, whose loyalty earned both of them a UQAM professorship of their own:

Jean-Benoit F Charron, Francois Ouellet, Mario Houde , Fathey Sarhan The plant Apolipoprotein D ortholog protects Arabidopsis against oxidative stress BMC Plant Biology (2008) doi: 10.1186/1471-2229-8-86 

Aneurus inconstans: “Figure 2a: two lanes appear twice within this figure (red boxes).”

In December 2025, Ouellet replied on PubPeer with: “This work was done 20 years ago, and some authors are retired.” Well, you and Houde aren’t retired, and Jean-Benoit Charron is now professor at McGIll university, so own up, boys. Oullet decided not to comment here:

Hélène Adam , François Ouellet , Ndjido A. Kane , Zahra Agharbaoui, Geneviève Major , Yoko Tominaga , Fathey Sarhan Overexpression of TaVRN1 in Arabidopsis promotes early flowering and alters development Plant and Cell Physiology (2007) doi: 10.1093/pcp/pcm089 

Elisabeth Bik: “Concern about Figure 3: Green boxes: panels I (Epidermal cells of flower sepal in OEX-P3 plant) and J (Epidermal cells of a cauline leaf in the WT) appear to overlap, with a rotation and a stretch.”

Here a set of two papers, where Houde lamented on PubPeer that “Some authors are retired including myself” and that he “did not keep contact with all authors and they will be hard to reach“:

Aneurus inconstans: “Figures 6A and 6C show overexpressing TaICE87 or TaICE41 plants (please note the labelling mistake in 6C to the bottom) exposed to freezing stress.
The same image of a WT control plant appears rotaed four times (red boxes) across figure 6A and 6C.
Moreover, several images also appear rescaled in Figures 6A of Diallo et al. 2010 […] where treatments and genotypes are different (controls WT and 35S::GUS, transgenic plants 35S::TaVRN-B2 Line1–Line3.”

Badawi et al 2008: “Two gel mobility shift assays are identical (red boxes), but are supposed to show the binding affinity between TaICE87 and MYC2a (Figure 4B), or between TaICE41 and MYC4g1 (Figure 4C).”

This UQAM fabrication, with Sarhan, his postdoc Hamel, and the UQAM professor Mircea Alexandru Mateescu, appeared in what used to be the official journal of the Canadian Society for Pharmaceutical Sciences, later on the journal was sold to Frontiers. Who’s responsible now? Nobody.

Patrick De Koninck, Denis Archambault, Francine Hamel, Fathey Sarhan , Mircea Alexandru Mateescu Carboxymethyl-starch excipients for gastrointestinal stable oral protein formulations containing protease inhibitors Journal of Pharmacy & Pharmaceutical Sciences (2010) doi: 10.18433/j3b01f 

Aneurus inconstans: “Two sets of lanes in Figure 1a appear to be much more similar than expected (red and yellow arrows).
Two bands in Figure 1b seem to appear twice (green arrows).”

Four years later, in 2014, Mateescu won the UQAM Research-Career Prize for research like this.

Here, we had the rare honour of Sarhan himself replying (well, not quite):

Ndjido A. Kane, Jean Danyluk , Guylaine Tardif , François Ouellet, Jean-François Laliberté , Allen E. Limin, D. Brian Fowler, Fathey Sarhan TaVRT-2, a Member of the StMADS-11 Clade of Flowering Repressors, Is Regulated by Vernalization and Photoperiod in Wheat Plant Physiology (2005) doi: 10.1104/pp.105.061762 

Aneurus inconstans : “The TaVRT-1 blots in Figure 4A and 4C are identical (red boxes), but the wheat lines are supposedly different.
Moreover, four bands of TaVRT-1 in 4B also appear in 4D (blue boxes).”

The comment was posted using Sarhan’s professional email address, but signed by the UQAM professor Jean Danyluk, whom you already met above:

Fathey Sarhan: “This article has been published 20 years ago and some of the authors are retired or difficult to reach. We are contacting the first author who did the experiment and the figure to provide the answer to your question. This should be very soon. Jean Danyluk”

Danyluk was Sarhan’s MSc and PhD student, he stayed on with Sarhan as postdoc, doing science like this, and eventually earned himself a professorship at UQAM:

Jean Danyluk, Ndjido A. Kane, Ghislain Breton , Allen E. Limin, D. Brian Fowler, Fathey Sarhan TaVRT-1, a putative transcription factor associated with vegetative to reproductive transition in cereals Plant Physiology (2003) doi: 10.1104/pp.103.023523 

Aneurus inconstans : “Figure 3: two lanes of the TaVRT-1 blot appear twice (red boxes).”
“Figure 7: blots of LD 0 and LD 49 are identical (red boxes).”
“The same TaTRV-1 blot appears in Figure 4A and 4D (blue boxes) for two different verieties of wheat. Red arrows indicate visible splices. The same rRNA control (green boxes) appears in Figure 4A, 4B and 6 for different varieties of wheat and barley. The same rRNA control (pink boxes) appears in Figure 4D and 6 for wheat and barley. Finally, the same band appears three times in the Hvbm5 blot of Figure 6 (blue arrows), where a clear splice is also visible (red arrow).”

I can’t prevent anyone from making Dicktoo jokes involving Sarhan and Danyluk. Here is another former postdoc of Sarhan’s shitposting – Ahmed Faik, now professor at Ohio University in USA:

Ahmed Faik , Jaouad Abouzouhair , Fathey Sarhan Putative fasciclin-like arabinogalactan-proteins (FLA) in wheat (Triticum aestivum) and rice (Oryza sativa): identification and bioinformatic analyses Molecular Genetics and Genomics (2006) doi: 10.1007/s00438-006-0159-z 

Aneurus inconstans “Three TaFLA14 bands of Figure 4 also appear in Figure 5 (red boxes). See contrast enhancement comparison to the right. Although the conditions are identical, the rRNA controls are different, therefore these are supposed to be different experiments.”

Faik assured on PubPeer:

Due to the age of the paper (20 years) the raw data is not available to be verified. However, this discrepancy is insignificant and doesn’t affect the impact of the paper.”

I start suspecting that everyone at UQAM suffered some kind of mysterious brain damage.


Donate!

If you are interested to support my work, you can leave here a small tip of $5. Or several of small tips, just increase the amount as you like (2x=€10; 5x=€25). Your generous patronage of my journalism will be most appreciated!

€5.00

3 comments on “The minor infractions by Diana and Fathey

  1. egle krosniunas's avatar
    egle krosniunas

    Your response to the outrageous “requests” of UQAM was perfect.

    Liked by 2 people

  2. anas platyrhynchos's avatar
    anas platyrhynchos

    Being an early career researcher, I often wonder how many “giants” in biosciences, people who published in the 80s, 90s, and 00s in Nature etc and had razor sharp significance, low p-values were actually fabricating either part or most of their data to hack it in a way so that it was appealing to funders and publishers? And now, when I do an experiment, there is batch-to-batch variability, day-to-day variability, assays that work only on a certain Wednesday, sudden changes in the personality of a cell-line, and NEVER that level of significance and low p-value?

    Like

Leave a comment