Two EMBO corrections for the martyred saint Maria Pia Cosma

Two EMBO corrections for the martyred saint Maria Pia Cosma

The cell biologist Maria Pia Cosma, top-funded and prize-winning professor in Barcelona, is either an indestructible zombie scientist or a martyred saint. Her name means in Italian Mary the Pious, so it is probably the latter. So the following post is written in the style of a canonical satire.

Holy Mary Pia was accused by evil tongues on PubPeer of research misconduct in several of her publications. Philistines pointed crooked fingers and cast stones at duplicated western blot bands in papers published by St. Maria Pia in exalted scriptures like Cell. The accusers, envious of such impact factors, wished those gospels of scientific truth crucified on the cross of retraction and demanded for Our Lady of Barcelona to be judged and investigated. Yet Lord took mercy upon the tortured saint and sent His angels to defend her.

The martyr of research integrity, St. Maria Pia (right, standing) receives a sign for “Beatified”. Source: Cosma lab, under fair use

Continue reading “Two EMBO corrections for the martyred saint Maria Pia Cosma”

With Voinnet and Cosma cover-up, Cell now admits to have no editorial integrity whatsoever

The elite journal Cell issued editorial notices in regard to 3 papers by the Swiss-based French plant scientist Olivier Voinnet (found guilty of research misconduct in many papers) and one by the Spain-based Italian cell biologist Maria Pia Cosma (some information about her papers here). The journal Molecular Cell (which editorial offices are not entirely independent from Cell) issued same note for a different Cosma paper.

Despite obvious data manipulations, the journal decided not to do even as little as a correction. This is in full agreement with a previous declaration by the Cell Editor-in-Chief Emilie Marcus, who announced one year ago to be tolerating data manipulations in her journal, provided the science described is “wow” and “cool” (see details in my satire article here). Indeed, as a branch of the private business Elsevier, Cell is free to publish whatever they wish, even explicit fraud, lies and fakery. It is however the duty of all scientists, funding agencies and the subscription-paying university libraries to decide if what Cell publishes is actually any good science under such policies.  Even if it reads“wow”.

I will simply list the four editorial notices below, accompanied with some corresponding images off PubPeer. Naturally, none of that author-provided evidence (i.e., where it existed in the first place) which Cell found so convincing, is shared with us nosy readers. Make your own judgement, the notices speak for themselves. Continue reading “With Voinnet and Cosma cover-up, Cell now admits to have no editorial integrity whatsoever”

The laborious delivery of Markram’s brainchild

The laborious delivery of Markram’s brainchild

The European multimillion research project Human Brain Project is under fresh leadership, its visionary founder Henry Markram ousted from power. Worse, both life-and-blood projects of the neuroscience professor at the Swiss elite university EPFL are not performing as he envisioned them to.  His open access publishing house Frontiers was dumped by the Nature Publishing Group and ended up with the German publisher Holtzbrinck, with neither them nor Frontiers particularly keen on boasting this property relationship. Editors and reviewers ran away or refused duty in droves, Frontiers was even fingered as a possible predatory publisher. On top of everything, Markram’s outlet stands accused of being an employee-abusing spam factory.

So much for Markram the Entrepreneur and Inventor. But he is first and foremost a scientist, whose research proposal received the biggest research funding grant in history: one billion Euros from the European Union, for his “brainchild” (as journalists dubbed it), the Human Brain Project. The modest promise Markram originally made to secure this mind-boggling mountain of cash: he intended to simulate the entire human brain in his supercomputer by 2023, the possibility of artificial consciousness specifically not excluded. Now however, his consortium partners took over, Markram was dethroned in a scientists’ coup and pushed aside to tinker on his seemingly less ambitious, but just as science-fictionary mouse Blue Brain simulation. Once in control of almost everything and everyone, with all the big money going through his hands, Markram is now only one of 12 project leaders and far from being the boss. The Human Brain Project (HBP) became instead a kind of funding network without any properly defined orientation, not even the new leaders could convincingly describe any defined goals. Instead, its main purpose seems to be now set on keeping the EU funding of almost €50 Million per year flowing. Remarkably, all this was achieved after an allegedly independent mediation by the director of an HBP-consortium partner institute; coincidentally a member scientist from this Jülich Research Centre (Forschungszentrum Jülich, located in a rural triangle between German cities Düsseldorf, Cologne and Aachen) is now the new scientific director of HBP.

This is how the dream of the brain-in-the-box grew, prospered and imploded. Continue reading “The laborious delivery of Markram’s brainchild”

Voinnet aftermath: ethical bankruptcy of academic elites

Voinnet aftermath: ethical bankruptcy of academic elites

Olivier Voinnet, the disgraced former star plant scientist and professor at ETH Zürich, is apparently on extended sick leave, his lab members have been redistributed to other research groups inside the faculty. This I learned from several independent sources, which made the information sufficiently reliable to share here. Previously, Voinnet was investigated by two expert commissions, one very secret by CNRS at his former Institut de Biologie Moleculaire des Plantes (IBMP), and another, more transparent one, at ETH (report here, my overview of the Voinnet scandal here). There, the investigative team comprised of four peers, two of whom were Voinnet’s faculty colleagues, and one was Witold Filipowicz, professor at Friedrich Miescher Institute in Basel. Filipowicz had been evaluating Voinnet’s research as IBMP review board member in 2008, before he nominated him for the 2009 EMBO Gold Medal:

“Olivier Voinnet’s discoveries represent true breakthroughs in his field. He has written several illuminating reviews recently, and participated as a speaker in many prestigious meetings. I consider him to be one of the most talented, original and effective young scientists”.

Update 8.04.2016: The supposedly impartial Voinnet investigator Filipowicz was also a recipient of the 2014 Chaire Gutenberg at Voinnet’s own IBMP as well as neighbouring IBMC in Strassbourg. The Gutenberg Chair is financed by the Alsace Region and the Urban Community of Strasbourg  with € 60,000 of which € 10,000 went to Filipowicz personally as ‘Gutenberg Prize’ and € 50,000 were awarded to his host, the teams of LabEx NetRNA of IBMP and IBMC. Coincidently, one of LabEx NetRNA teams is still headed by Voinnet’s  IBMP lab keeper and key partner in data manipulation, Patrice Dunoyer.

Under such conditions, it is hardly surprising that the ETH investigative commission concluded that Voinnet’s research was still largely reliable, despite his inexplicably compulsive urge to manipulate his perfectly good experimental data. As ETH press release then announced, Voinnet research was “Conducted properly – published incorrectly”. Well, this depends what ETH leadership understands under proper research.

Below I will show evidence from Voinnet’s peers that the published experimental evidence for his bold discoveries was shaky even before the data manipulations were discovered. Finally, I could not find a single lab which could confirm to me that they reproduced his results. Continue reading “Voinnet aftermath: ethical bankruptcy of academic elites”

Is EMBO funding misconduct?

This is a NEWS post.

My Twitter feed recently showed that the highly respected European research organisation, EMBO, is funding a scientist directly associated with possible misconduct and data manipulation.

EMBO has announced on December 8th: Nine scientists receive EMBO Installation Grants, each of the nine recipients is also to obtain the prestigious title of EMBO Young Investigator.

The problematic scientist in question is the Portuguese Sónia Melo, with research interest in “Exosomes in intra-tumor heterogeneity”. She is returning to Europe from the MD Anderson Cancer Center, Houston, US, and is to receive from EMBO the funding of ” 50,000 Euros annually for three to five years” for her new lab in University of Porto, Portugal.

Indeed, Melo’s publication list is stellar, her sheer impact factor justifies every possible research grant. Or does it? Are image duplications any kind of concern for EMBO, especially those strangely rotated and flipped ones, which can very unlikely happen due to negligence or technical error? Continue reading “Is EMBO funding misconduct?”