satire

The Passion of Don Carlos

I obtained a partial script of a stage play which recently premiered in Paris: "La Passion de Don Carlos". Any similarities with Spanish or French cancer researchers are entirely coincidental.

I obtained a partial script of a stage play which recently premiered in Paris. The original was written and performed in French, its title is “La Passion de Don Carlos”and rumours go the lead role was played by none other but Antonio Banderas!

In the centre is a romantic triangle, at the background of international cancer research, with murder, money and religion thrown in the mix. Valentine’s Day is over, and April 1st is still weeks away, but I decided to publish it the drama script now, what with the events in Spain. What I have here is a poor English translation, but I hope you like it anyway. Apparently, any similarities with Spanish or French cancer researchers are entirely coincidental.

La Passion de Don Carlos

Main Characters:

Carlos, a Spanish star scientist on sabbatical in France

Guido, another eminent cancer researcher, of German origin, and Carlos’ host

Laurence, French scientist, life partner and scientific collaborator of Guido

KroemerLab

Set: Bedroom, time: late evening. Carlos is lying in bed wearing pajamas, Laurence, dressed casually and in “KroemerLab” T-shirt, sits next to him holding his hand. Door opens, Guido walks in, dressed smart, tie loosened.

Guido:

Liebling, what a party! Eighty years CNRS and you missed it! So much booze I had to run to gents and guess whom I see there? Catherine! She was kicking that nasty Le Monde journo, and guess who was holding him in the headlock? Antoine! You know he is not petit at all, Antoine: big guy, used to play rugby. So Cathy is kicking that journo while Antoine holds him tight, I think she specially put on her pointiest shoes, and then she turns around, sees me, smiles and says: Don’t you worry Guido. I will make sure you won’t retract a single paper. Kisses to Carlos, she also said. Carlos? Carlos, you asleep? What are you doing in our bed, amigo?

Laurence:

Carlos is unwell. He keeps waking up, screaming “putos ratones”, I think he has nightmares. He will stay in our bed, Guido. You will rest now, right, Carlos?

Carlos:

Si. Very cushy pajamas, thanks Guido.

Guido:

What was wrong with the couch, Carlos? Laurence, we can’t sleep on the couch in our own home!

Laurence:

You will be sleeping on the couch, Guido. Just you. Carlos is very unwell, he needs company. Besides, he teaches me the Photoshop.

Guido:

The Photoshop? I taught you all there is to know about The Photoshop, remember? This was how we met, Liebling! You forgot how I showed you [makes quotation marks with fingers] the secret to big science? What do you need Carlos’ ham-fisted blot cloning for? I made up stuff those morons on PubPeer will never notice, in their entire pathetic lives! Even Catherine was impressed when I told her. Laurence, remember how we first collaborated, was it what, twenty years ago? We did it all, long before Photoshop became cool and I showed you all the tricks there are, this was when you fell in love with me! You used to call me your Blot Maestro! And, by the way, [turns to Carlos] none of my papers were ever retracted.

Carlos:

That hurt my friend. If you don’t like me being here, I can take my suitcases elsewhere. Including that [makes quotation marks with fingers] Eee-Arr-See suitcase, you know? Guido?

Laurence:

Boys, stop. Friends again now. This is serious business, I keep getting those phone calls from Brussels, they ask if I know where the money is. Carlos, lie down again. These mice are all dead now, they can’t hurt you anymore, you are safe.

Guido:

Oh yeah, the mice! How was the trip to Oviedo, Carlos? Did the little rodents meet with some [coughs falsely] unfortunate accident? Did Suarez do as you asked? [makes a cut-throat sign]

Carlos:

Si, all dead. But I killed them myself, with my own two hands! [lifts his hands, which are trembling] Six thousand of them, I think I accidentally also killed mice belonging to other people… It was horrible, I worked through the entire night, alone… I was in that rage you know, couldn’t read cage labels anymore.… When I thought I couldn’t do it anymore, I gave mice the names of certain people before I did them, it helped… I think I almost strangled some Pomeranian on my way from Bioterio, the owner hit me with her handbag, an old lady… Had to run from the police then…

Laurence:

You poor man, you did it all alone, through the night? Was nobody there to help you?

Carlos:

[shakes his head, he lies down again]. I am telling you, I was alone. All night. They are all dead now. Suarez now takes care of the story, that pathetic chickenshit.

Guido:

Was Suarez not supposed to help you? He said he would.

Carlos:

Suarez is a wimp. First mouse bites him, he cries like a little girl and runs out. Sat then in the corner quivering, all night while I did the job. [shouts] Putos ratones!

Guido:

So sorry, Carlos. If I knew, I would have come with you to Oviedo. I love destroying evidence [winks at Laurence, who smiles knowingly]

Door rings. Guido walks out to answer. One hears someone indistinctly speaking Spanish,

Guido:

[answers first in Spanish, indistinctly, then calls out] I didn’t expect the Spanish Inquisition!

Slap in a face is heard, Guido shouts out in pain. Enter three men dressed very much like the Monty Python characters from the Spanish Inquisition sketch.

Inquision Men #1-3

[chanting]: Pie Jesu domine, dona eis requiem. Pie Jesu domine, dona eis requiem

Inquisition Man #1:

[to Carlos] Hola Don Carlos, finalmente!

Guido :

[walks in, rubbing his cheek] They say they are Asturian journalists and want to interview you [turns to Carlos] but [to Laurence] I think they are actually Opus Dei or something…

    Inquisition Man #1

[turns and lifts a finger at Guido] Cuidado, cabron.

Inquisition Men walk over to Carlos, the four whisper indistinctly in Spanish. Inquisition Man #1 points at Guido.

Carlos:

Él esta bien. Un Alemán.

Inquisition men nod approvingly.

Inquisition Man #1:

[says something else, indistinctly, to Carlos, then points backward with his thumb at Laurence] Zitvogel?

Guido:

[hastily] Oh-oh, no no no, señores. Ella non es Zitvogel. Ella es Frau Laurence zu Vogelstein, we are all good Christian Catholics here!

Inquisition men nod and return to murmuring indistinctly in Spanish with Carlos.

Laurence:

What are you talking about dear? You are German, I am not! I am….

Guido:

Liebling, sei ruhig! These men are [whispers] Opus Dei! [Inquision men turn around and look at Guido with suspicion] I mean what honour for us three good Catholics to have Opus Dei here! Wine anyone? Coffee? Have we got any biscuits, Frau?

Laurence:

I thought you said they were journalists from Asturia? And why do I have to hide that I am…

Guido:

[forms praying sign imploring Laurence] Liebling, they are special journalists, they came to interview Carlos for La Nueva Inquisición [angry glance from Inquisition man #1] I mean La Nueva Espana, Senor Alvarez! [To Laurence] Now help me get us all coffee like a good Catholic wife you are. Schnell, raus.

Guido and Laurence exit the bedroom to another end of the stage where the kitchen is. Carlos and Inquisition Men, who climb into his bed, remain seen in the background. They all hold rosaries and are heard murmuring, with occasional fragments of Hail Mary and Our Father prayers, in Spanish.

Laurence:

Guido, I will not be portrayed in my own house as some German Frau zu Vogelstein!

Guido:

It’s for Carlos, his Spanish friends are… a bit conservative. Thank God you are blonde, Frau zu Vogelstein or they would never have believed me… Coffee?

They make coffee and sit down with cups, at some point Inquisition Men are seen getting out of bed, exchanging cheek kisses with Carlos and leaving. Carlos jumps out of bed and runs into the kitchen, waving a rosary.

Carlos:

Friends, great news! They explained it to me! The Devil did it! I was possessed by Satan! Dios mio, Hallelujah!

Laurence:

Carlos, you are unwell. You have a fever and you are raving. Please go back and lie down.

Guido:

Yes Carlos, take the couch [Laurence glances at Guido]. I mean, take the bed. I will sleep on the couch. Which Satan were you talking about, that blogger troll?

Carlos:

The real Satan, el Diablo! I didn’t want to believe it myself, but it makes sense! The Devil meddled into my science, soiled my papers and brought me the retractions. The Devil screwed up my transgenic mice, and then made me kill them! I was possessed, mis amigos! [falls on his knees and prays, clutching his rosary] Dios te salve, María, llena eres de gracia, el Señor es contigo. Bendita tú eres entre todas las mujeres,y bendito es el fruto de tu vientre, Jesús. Santa María, Madre de Dios….

Laurence:

Carlos… Carlos… get up… It can’t be. We all do a bit of Photoshop now and then, it’s fun. It’s not a sin, it’s science. Here in France, we celebrate it. Right, Guido? You saw Catherine tonight, right? What did she say?

Guido:

She said not to worry and sent kisses to Carlos. And Antoine gave me a thumbs-up I think. Carlos, get up. Let’s all Photoshop together, right now. Let’s make a Cancer Cell paper, all three of us! Nah, let’s do Cell proper, that will show everyone! They like Photoshop there and never retract anything [beaming first at Carlos, then at Laurence, who smiles back]

Carlos:

[gets up and sits down at kitchen table] Later, maybe. I made up my mind. Tomorrow I’ll go back to Oviedo. We will do exorcism. They will bring someone from Navarra, a specialist. Same guy who did Gosalvez back in the eighties, he must be like hundred now, ancient, like Lonesome George, you know, that tortoise [sighs]…  but he will come to Oviedo to save me and then bless my whole lab. The exorcist, not the tortoise. And even bless that fucking Bioterio, Alvarez said they would even pray for the mice!

Guido:

Exorcism? What a strange idea Carlos. How much do these Opus people charge anyway?

Carlos:

They don’t charge, Guido, don’t you blaspheme here! There will surely be enough in that [makes quotation marks with fingers] Eee-Arr-See suitcase for a small caritative donation, OK? [Guido makes a worried face] Enough will remain for us all, friends. Oh, it will be great. I want all my friends to be there at my exorcism. Margarita will sure come. Come also!

Laurence:

If it makes you feel better Carlos… Would you like a chamomile tea? [handles Carlos a cup] Shall we also go to Oviedo, Guido? I sure would like to see an exorcism show!

Guido:

Ahem… Laurence, you can’t go… [to Carlos] Her [makes quotation marks with fingers] tribe is you know… not welcome with Opus. Not sure I can pull off that Frau zu Vogelstein trick again… But I will come!

Carlos:

Brilliant! Like the old times, Guido, you and I, doing our thing together! Everything will be allright afterwards, back like it used to. Let’s pack our suitcases!

Guido:

But not THAT suitcase, Carlos!

Guido, Carlos and Laurence laugh and cheer each other with cups.

 

Curtains.

 


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24 comments on “The Passion of Don Carlos

  1. I know of a certain PI from Cornell…but different from Carloshe never puts his hands on the mice…he has the whole lab to take good care of the mice and never comes in the emails…so this story is quite representative of many labs with different nuances

    Like

  2. No one respects the Spanish Inquisition. Our main weapons are whitewash, mediocrity and a fanatical devotion to …. good lord, what’s that awful smell? Like a truckload of dead ratones…….

    Like

  3. Ay Leonidas…eres un payaso…y de los malos…un preescolar tendría más gracia.
    For better Science, really?

    Like

  4. Dark Avenger

    Meride smells the same in any language. Lopez-Otin esta burlador se Espana.

    Like

  5. When does the Commendatore appear and drag them all down to hell with an army of mice?
    Or is that Act II?

    Like

  6. Uniovi rector explains that they are reducing non professional staffs and increasing postdocs and assistant professors.
    So identified who are alledged internal Trolls in the Department to fire? And bringing back first authors of retracted Nature Cell Biology (Soria-Valles and Osorio, 2015) from Harvard to build a strong productive team?
    “El Rector también resaltó el esfuerzo que está realizando la Universidad por reducir el número de asociados no profesionales e impulsar las figuras de ayudante y contratado doctor para rejuvenecer la plantilla desde los niveles más bajos.”
    https://cadenaser.com/emisora/2019/02/20/radio_asturias/1550667483_835934.amp.html?__twitter_impression=true

    Like

    • They simply would like to contract cheaper workers – that’s it. Instead of getting associate professors, they get assistant (some of them part-time) to teach and cover the teaching hours of the professors who retired.

      Like

  7. Santiago García Granda about Lopez-Otin: …”it is certainly the flagship of the University of Oviedo and it would be very worrying if he left the University “.

    I would rather call it a rat ship.

    Like

  8. Cercei Lannister

    [edited, LS] the evidence of fraud, data fabrication and clumsy image manipulations are so damn huge, that local scientific authorities and newspapers, if not opening their mouths to condemn it because they want to avoid more damage to the person, then at least they should have stayed shut up, instead of this tremendous, mediatic defense campaign. It’s a shame. Shame… Shame… (as in GoT 6×10… LOL)
    Now they’re back with a paper in Nature Medicine (https://www.nature.com/articles/s41591-018-0338-6).
    I guess after all this via crucis he (they) have extremed care with figure preparation, or at least, instead of clumsy ‘copy-paste-180rotate-invert’ they did with MS Paint, they now have come up with advanced and more discrete image processing softwares (LOL).
    Nevertheless, let’s give a close look to this work, because more grants are coming, more fellowship fundings, more tenure-track positions in the University… and many, if not all of them, are paid by Spanish taxpayers’ euros. And there are many decent, honest, hard-working scientists in Spain that deserve this fundings in the first place.

    Like

  9. This time for the Nature Medicine, Lopez-Otin people become quite careful to figure preps.
    For those who want to take closer look at source numerical data, images and blots, here is the link.
    https://www.nature.com/articles/s41591-018-0338-6#Sec17

    Like

  10. “Too many papers” in Spain.
    https://elpais.com/elpais/2019/02/18/ciencia/1550484222_682428.html
    Indeed, there are too many papers from Lopez-Otin students.
    The first author of the retracted Nature Cell Biology article Clara Soria-Valles published seven first author papers during 2014-2017. Almost of original articles from Soria-Valles are PubPeer marked.

    Immune and inflammatory responses to DNA damage in cancer and aging.
    Soria-Valles C, López-Soto A, Osorio FG, López-Otín C.
    Mech Ageing Dev. 2017 Jul;165(Pt A):10-16. doi: 10.1016/j.mad.2016.10.004. Epub 2016 Oct 5. Review.
    PMID: 27720808
    Novel LMNA mutations cause an aggressive atypical neonatal progeria without progerin accumulation.
    Soria-Valles C, Carrero D, Gabau E, Velasco G, Quesada V, Bárcena C, Moens M, Fieggen K, Möhrcken S, Owens M, Puente DA, Asensio Ó, Loeys B, Pérez A, Benoit V, Wuyts W, Lévy N, Hennekam RC, De Sandre-Giovannoli A, López-Otín C.
    J Med Genet. 2016 Nov;53(11):776-785. doi: 10.1136/jmedgenet-2015-103695. Epub 2016 Jun 22.
    PMID: 27334370
    iPSCs: On the Road to Reprogramming Aging.
    Soria-Valles C, López-Otín C.
    Trends Mol Med. 2016 Aug;22(8):713-724. doi: 10.1016/j.molmed.2016.05.010. Epub 2016 Jun 7. Review.
    PMID: 27286740
    MMP-25 Metalloprotease Regulates Innate Immune Response through NF-κB Signaling.
    Soria-Valles C, Gutiérrez-Fernández A, Osorio FG, Carrero D, Ferrando AA, Colado E, Fernández-García MS, Bonzon-Kulichenko E, Vázquez J, Fueyo A, López-Otín C.
    J Immunol. 2016 Jul 1;197(1):296-302. doi: 10.4049/jimmunol.1600094. Epub 2016 Jun 3.
    PMID: 27259858
    1 comment on PubPeer. https://pubpeer.com/publications/46D48D7AB88DC28DD57C0CC1BF8DF9
    Reprogramming aging through DOT1L inhibition.
    Soria-Valles C, Osorio FG, López-Otín C.
    Cell Cycle. 2015;14(21):3345-6. doi: 10.1080/15384101.2015.1093443. No abstract available.
    PMID: 26375309
    3 comments on PubPeer. https://pubpeer.com/publications/4C15A69C70155586425CCA77813E58
    RETRACTED. NF-κB activation impairs somatic cell reprogramming in ageing.
    Soria-Valles C*, Osorio FG*, Gutiérrez-Fernández A, De Los Angeles A, Bueno C, Menéndez P, Martín-Subero JI, Daley GQ, Freije JM, López-Otín C. Soria-Valles and Osorio contributed equally.
    Nat Cell Biol. 2015 Aug;17(8):1004-13. doi: 10.1038/ncb3207. Epub 2015 Jul 27. Retraction in: Nat Cell Biol. 2018 Dec 17;:.
    PMID: 26214134
    155 comments on PubPeer. https://pubpeer.com/publications/836AB3A8AB4FD562A2D4CBFBF8ED18
    The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21.
    Soria-Valles C, Gutiérrez-Fernández A, Guiu M, Mari B, Fueyo A, Gomis RR, López-Otín C.
    Oncogene. 2014 Jun 5;33(23):3054-63. doi: 10.1038/onc.2013.267. Epub 2013 Jul 15.
    PMID: 23851508
    3 comments on PubPeer. https://pubpeer.com/publications/8D0F4C1D83621DE5F72E92A4C39787

    The co-first author of the retracted Nature Cell Biology article Fernando G. Osorio published eleven first author papers during 2009-2016. Osorio is the second author of the recent Nature Medicine article, his role in which was to conceive and conduct the experiments.

    The novel tumor suppressor AIRAPL regulates IGF1R proteostasis.
    Osorio FG, Freije JM, López-Otín C.
    Cell Cycle. 2016;15(7):873-4. doi: 10.1080/15384101.2016.1151725. Epub 2016 Feb 22. No abstract available.
    PMID: 26901531
    NF-κB signaling as a driver of ageing.
    Osorio FG, Soria-Valles C, Santiago-Fernández O, Freije JM, López-Otín C.
    Int Rev Cell Mol Biol. 2016;326:133-74. doi: 10.1016/bs.ircmb.2016.04.003. Epub 2016 May 30. Review.
    PMID: 27572128
    Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.
    Osorio FG, Soria-Valles C, Santiago-Fernández O, Bernal T, Mittelbrunn M, Colado E, Rodríguez F, Bonzon-Kulichenko E, Vázquez J, Porta-de-la-Riva M, Cerón J, Fueyo A, Li J, Green AR, Freije JM, López-Otín C.
    Nat Med. 2016 Jan;22(1):91-6. doi: 10.1038/nm.4013. Epub 2015 Dec 21.
    PMID: 26692333
    RETRACTED. NF-κB activation impairs somatic cell reprogramming in ageing.
    Soria-Valles C*, Osorio FG*, Gutiérrez-Fernández A, De Los Angeles A, Bueno C, Menéndez P, Martín-Subero JI, Daley GQ, Freije JM, López-Otín C. Soria-Valles and Osorio contributed equally.
    Nat Cell Biol. 2015 Aug;17(8):1004-13. doi: 10.1038/ncb3207. Epub 2015 Jul 27. Retraction in: Nat Cell Biol. 2018 Dec 17;:.
    PMID: 26214134
    155 comments on PubPeer. https://pubpeer.com/publications/836AB3A8AB4FD562A2D4CBFBF8ED18
    Luminescence-based in vivo monitoring of NF-κB activity through a gene delivery approach.
    Osorio FG, de la Rosa J, Freije JM.
    Cell Commun Signal. 2013 Mar 21;11(1):19. doi: 10.1186/1478-811X-11-19.
    PMID: 23517552
    NF-kB in premature aging.
    Osorio FG, López-Otín C, Freije JM.
    Aging (Albany NY). 2012 Nov;4(11):726-7. Review. No abstract available.
    PMID: 23211391
    Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response.
    Osorio FG, Bárcena C, Soria-Valles C, Ramsay AJ, de Carlos F, Cobo J, Fueyo A, Freije JM, López-Otín C.
    Genes Dev. 2012 Oct 15;26(20):2311-24. doi: 10.1101/gad.197954.112. Epub 2012 Sep 26.
    PMID: 23019125
    18 comments on PubPeer. https://pubpeer.com/publications/4E89FBEE8E6605B592593CF801E7BD
    Cell autonomous and systemic factors in progeria development.
    Osorio FG, Ugalde AP, Mariño G, Puente XS, Freije JM, López-Otín C.
    Biochem Soc Trans. 2011 Dec;39(6):1710-4. doi: 10.1042/BST20110677. Review.
    PMID: 22103512
    Splicing-directed therapy in a new mouse model of human accelerated aging.
    Osorio FG, Navarro CL, Cadiñanos J, López-Mejía IC, Quirós PM, Bartoli C, Rivera J, Tazi J, Guzmán G, Varela I, Depetris D, de Carlos F, Cobo J, Andrés V, De Sandre-Giovannoli A, Freije JM, Lévy N, López-Otín C.
    Sci Transl Med. 2011 Oct 26;3(106):106ra107. doi: 10.1126/scitranslmed.3002847.
    PMID: 22030750
    Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease.
    Osorio FG, Varela I, Lara E, Puente XS, Espada J, Santoro R, Freije JM, Fraga MF, López-Otín C.
    Aging Cell. 2010 Dec;9(6):947-57. doi: 10.1111/j.1474-9726.2010.00621.x. Epub 2010 Oct 21.
    PMID: 20961378
    Accelerated ageing: from mechanism to therapy through animal models.
    Osorio FG, Obaya AJ, López-Otín C, Freije JM.
    Transgenic Res. 2009 Feb;18(1):7-15. doi: 10.1007/s11248-008-9226-z. Epub 2008 Nov 18. Review.
    PMID: 19015945

    Like

  11. Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome
    Nature Medicine (2019) – 1 Comment
    pubmed: 30778239 doi: 10.1038/s41591-018-0338-6 issn: 1078-8956 issn: 1546-170X

    Olaya Santiago-Fernández , Fernando G. Osorio , Víctor Quesada , Francisco Rodríguez , Sammy Basso , Daniel Maeso , Loïc Rolas , Anna Barkaway , Sussan Nourshargh , Alicia R. Folgueras , José M. P. Freije , Carlos López-Otín

    https://pubpeer.com/publications/990AE6C60FE817D66B24B7CD25B89F

    “Two questions to fig.1e.
    How to define nuclear defects? The arrowhead in the image supposed to indicate nuclear defect (aberrations). But it is not clear on the provided image. The ones I circled in red cannot see aberrations. Can the authors provide higher magnification images?
    Scoring strategy. The source data indicated very close counts among three independent infection experiments. And the reporting summary described that the counts were done in blinded manner. However, due to uncertain definition of nuclear defect which depends on subjective scoring, I wonder why each independent experiment gave such similar counts.”

    https://pubpeer.com/publications/83246749B705D3DF9C468C938AFC61

    “The mouse strain Lmnatm1.1Otin, used in this study, was originally developed in 129P2/OlaHsd background by the Lopez-Otin lab. http://www.informatics.jax.org/allele/MGI:5295747 The strain was backcrossed to C57BL/6N according to the reporting summary of this article.
    A study from Ron Khan described that strain difference between 129 and B6 matters in metabolism and ageing research. “By studying B6 versus 129 mice at different ages and on different diets, one may therefore elucidate the back- ground inherited phenomena predisposing to obesity-accompanied insulin resistance” http://diabetes.diabetesjournals.org/content/59/11/2960
    Lmnatm1.1Otin mouse either in 129 or B6 background is not available from IMSR, “Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available ” Could the authors deposit this strain for community, and describe if background difference matters?”

    Like

  12. So, the Nature Medicine paper was dressed more carefully, but still there could be the same pattern of issues as retracted Nature Cell Biology paper (Soria-Valles, 2015)? Uncertain subjective counts and probably lack of samples (all mice dead?). Let me just point out the coincidence that the second author of this Nature Medicine paper, Fernando G. Osorio, was the co-first author of the retracted Nature Cell Biology paper.

    Like

  13. It’s not as if you are ever going to be able to correct every cell in a patient using CRISPR anyway, so the title is a bad joke, dead mice or not. This is the scientific equivalent of clickbait, which sadly is all Nature seems interested in anymore.

    Like

  14. Can someone teach us how the system of Juan de la Cierva incorporacion works? Does the money go to university or the lab then payed to the recipient as salary? Or the money directly goes to the pocket of the recipient? Is it technically possible that the recipient receive the money and never belong to any lab or not appear in the lab? I think it is totally corrupt scheme of which Soria-Valles secured own fund with retracted paper and bring the money to Lopez-Otin lab.

    Like

    • hakuna matata

      The money comes from the central science administration and goes to the university, then the latter commit through a contract to pay the researcher’s salary for the duration of the fellowship,which for the Juan de la Cierva is 3 years. To the best of my knoledge, there’s no way the money could go directly to the researcher nor him/her being paid any salary if doesn’t show up. There is a time window for incorporation after having been granted, though, sometimes up to 6 months.

      Like

  15. Lopez-Otin is coming back to uniovi on Monday, March 4th. Uniovi mentioned that ‘harassment’ started from October 2017. They have not identified any individual or legal entity who could be accused of harassment in legal terms. ERC has requested uniovi for information after the withdrawal of the nine articles.

    https://www.lavozdeasturias.es/noticia/asturias/2019/03/01/lopez-otin-vuelve-lunes-dar-clase-universidad-oviedo/00031551463806983142382.htm

    López-Otín vuelve este lunes a dar clase en la Universidad de Oviedo
    El catedrático del área de Bioquímica y Biología Molecular regresa de su estancia sabática en París

    English
    “López-Otín returns on Monday to teach at the University of Oviedo
    The professor of the area of ​​Biochemistry and Molecular Biology returns from his sabbatical stay in Paris”

    El catedrático en el área de Bioquímica Y Biología Molecular en el departamento de Bioquímica de la Universidad de Oviedo, Carlos López Otín (Sabiñánigo, Huesca, 1958), volverá este lunes día 4 de marzo a impartir clases en la Universidad de Oviedo tras una estancia sabática de meses en París. Así lo ha confirmado el rector de la Universidad de Oviedo, Santiago García Granda, al ser preguntado por el investigador. En la comparecencia ha estado acompañado por la gerente de la institución, Ana Caro Muñoz, el vicerrector de Organización Académica, Juan José del Coz, y el vicerrector de Investigación, José Ramón Obeso.

    English
    “The professor in the area of ​​Biochemistry and Molecular Biology in the Department of Biochemistry of the University of Oviedo, Carlos López Otín (Sabiñánigo, Huesca, 1958), will return on Monday, March 4 to teach at the University of Oviedo after a stay sabbatical of months in Paris. This has been confirmed by the rector of the University of Oviedo, Santiago García Granda, when asked by the researcher. At the hearing he was accompanied by the institution’s manager, Ana Caro Muñoz, the vice-chancellor of Academic Organization, Juan José del Coz, and the Vice-Rector for Research, José Ramón Obeso.”

    En declaraciones a raíz de las noticias relativas a la retirada de un artículo de su equipo en Nature Cell Biolog y otros ocho en Journal of Biological Chemistry por irregularidades en algunas imágenes, Otín reveló que llevaba siendo víctima de un acoso insoportable. Explicó que esa situación le llevó incluso a estar de baja y a irse a París.Tanto el rector como el resto de directivos han sido preguntados en varias ocasiones por la fecha desde la que conocían esa situación de acoso. Respondieron que fue alrededor de octubre de 2017 cuando empezaron a examinar las «acusaciones» que estaban recibiendo contra las publicaciones de su equipo de investigación.

    English
    “In statements following the news regarding the withdrawal of an article from his team in Nature Cell Biolog and eight others in the Journal of Biological Chemistry for irregularities in some images, Otín revealed that he had been the victim of unbearable harassment. He explained that this situation led him to be out of work and to go to Paris. Both the rector and the rest of the directors have been asked several times for the date they knew about this harassment situation. They replied that it was around October of 2017 when they began to examine the “accusations” they were receiving against the publications of their research team.”

    Sobre las medidas que había tomado la Universidad ante esa situación, Obeso explicó que le ofrecieron todo su apoyo y que Otín no solicitó más allá de apoyarle en sus planteamientos, que consideran correctos. En cuanto a si la Universidad tenía identificados a los acosadores o acosador, ha dicho que son personas privadas y que la institución estaría al lado de Otín si quisiera ejercer cualquier tipo de acción.

    English
    “On the measures taken by the University in this situation, Obeso explained that they offered their full support and that Otín did not ask for more than to support him in his proposals, which they consider correct. As to whether the university had identified the stalkers or stalker, he said that they are private persons and that the institution would be next to Otín if he wanted to take any kind of action.”

    Solicitud de información de ERC
    Posteriormente, los directivos de la Universidad de Oviedo han querido aclarar que ellos no tienen identificado a ninguna persona física o jurídica a quien se le pueda acusar de acoso en términos jurídicos. Por otro lado, la Universidad de Oviedo ha confirmado a Europa Press que European Research Council (ERC) se ha puesto recientemente en contacto con la institución para solicitarles información tras la retirada de los artículos mencionados. En abril de 2017 una propuesta liderada por Otín consiguió una ayuda Advanced Grants, de casi 2,5 millones para desarrollar un proyecto sobre el envejecimiento de mecanismos moleculares.

    Otín ha vuelto a ser noticia recientemente, cuando publicó un nuevo artículo científico en la revista Nature Medicine, relativo a una terapia basada en la edición génica para el tratamiento del síndrome de envejecimiento acelerado de Hutchinson- Gilford. La revista también publica un articulo que diseña otra terapia similar realizado por el equipo de Juan Carlos Izpisúa-Belmonte, del Instituto Salk.

    English
    “Request for information from ERCP
    Afterwards, the directors of the University of Oviedo wanted to clarify that they have not identified any individual or legal entity who could be accused of harassment in legal terms. On the other hand, the University of Oviedo has confirmed to Europa Press that the European Research Council (ERC) has recently contacted the institution to request information after the withdrawal of the aforementioned articles. In April 2017, a proposal led by Otín obtained an Advanced Grants aid of almost 2.5 million to develop a project on the aging of molecular mechanisms.

    Otín has made news again recently, when he published a new scientific article in the journal Nature Medicine, concerning a gene-based therapy for the treatment of the accelerated aging syndrome of Hutchinson-Gilford. The magazine also publishes an article that designs another similar therapy carried out by the team of Juan Carlos Izpisúa-Belmonte, of the Salk “

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