Cardiff investigates two cancer research professors for data manipulation

Cardiff investigates two cancer research professors for data manipulation

The Cardiff University in UK is now investigating two cancer researchers, both senior professors, for suspected scientific misconduct. The evidence was submitted by pseudonymous Clare Francis, I publish below the results of preliminary investigations. One of these two professors is Robert Nicholson, specialist in breast cancer, former director of Tenovus Centre for Cancer Research, now professor of Cardiff School of Pharmacy & Pharmaceutical Sciences, celebrated on BBC in 2008 for discovering a therapy target for tamoxifen-resistant tumours. The other is Wen Jiang, professor of Surgery and Tumour Biology at Cardiff University School of Medicine specialising in metastatic solid tumours, Fellow of Royal Society of Medicine and chair of Cardiff China Medical Research Collaborative. Jiang also made it into BBC news in 2013, when he announced to have discovered a “formula”, “consisting of 14 herbs” from traditional Chinese medicine, to stop cancer metastasis.

The two great doctors Jiang and Nicholson made great promises to cancer patients. A preliminary investigation by Cardiff University now determined that those promises were based on duplicated images and cloned gel bands. Importantly, the committee also saw irregular splicing of gels as a problem, an issue many tend to dismiss. The traditional excuse goes that gel splicing was allegedly permitted until 2008 or so. In fact, irregular splicing of gels, where bits of different gels are assembled to look as it were one intact physical gel, was never permitted and always considered to be data manipulation. Especially where due to splicing the gel loading controls are proven not to match the analytic gels, the entire figure becomes meaningless. Or worse, it indicates research misconduct. Continue reading “Cardiff investigates two cancer research professors for data manipulation”